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应用同种异体骨和自体骨移植联合修复颅面创伤后上颌牙槽嵴的组织形态学和临床评估

Histomorhological and clinical evaluation of maxillary alveolar ridge reconstruction after craniofacial trauma by applying combination of allogeneic and autogenous bone graft.

作者信息

De Ponte Francesco Saverio, Falzea Roberto, Runci Michele, Siniscalchi Enrico Nastro, Lauritano Floriana, Bramanti Ennio, Cervino Gabriele, Cicciu Marco

机构信息

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, AOU Policlinico "G. Martino", Via C. Valeria 98100 Messina, Italy.

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, AOU Policlinico "G. Martino", Via C. Valeria 98100 Messina, Italy.

出版信息

Chin J Traumatol. 2017 Feb;20(1):14-17. doi: 10.1016/j.cjtee.2016.10.005. Epub 2017 Jan 20.

Abstract

A variety of techniques and materials for the rehabilitation and reconstruction of traumatized maxillary ridges prior to dental implants placement have been described in literature. Autogenous bone grafting is considered ideal by many researchers and it still remains the most predictable and documented method. The aim of this report is to underline the effectiveness of using allogeneic bone graft for managing maxillofacial trauma. A case of a 30-year-old male with severely atrophic maxillary ridge as a consequence of complex craniofacial injury is presented here. Augmentation procedure in two stages was performed using allogeneic and autogenous bone grafts in different areas of the osseous defect. Four months after grafting, during the implants placement surgery, samples of both sectors were withdrawn and submitted to histological evaluation. On the examination of the specimens, treated by hematoxylin and eosin staining, the morphology of integrated allogeneic bone grafts was revealed to be similar to the autologous bone. Our clinical experience shows how the allogeneic bone graft presented normal bone tissue architecture and is highly vascularized, and it can be used for reconstruction of severe trauma of the maxilla.

摘要

文献中描述了多种在种植牙植入前用于创伤性上颌牙槽嵴修复和重建的技术及材料。许多研究人员认为自体骨移植是理想的方法,它仍然是最可预测且有文献记载的方法。本报告的目的是强调使用异体骨移植治疗颌面创伤的有效性。本文介绍了一例30岁男性因复杂颅面损伤导致严重萎缩性上颌牙槽嵴的病例。在骨缺损的不同区域分两阶段进行了异体骨和自体骨移植的增强手术。移植四个月后,在种植牙植入手术期间,取出两个区域的样本并进行组织学评估。在对苏木精和伊红染色处理的标本进行检查时,发现整合的异体骨移植的形态与自体骨相似。我们的临床经验表明,异体骨移植呈现出正常的骨组织结构且血管化程度高,可用于上颌严重创伤的重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acb6/5343098/8fcbae27ea38/gr1.jpg

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