Kuhls T L, Viker S, Parris N B, Garakian A, Sullivan-Bolyai J, Cherry J D
Am J Public Health. 1987 Oct;77(10):1306-9. doi: 10.2105/ajph.77.10.1306.
We have prospectively followed for 9-12 months, 246 female health care workers (HCWs): 102 with high exposure (HE), 43 with low exposure (LE), and 101 with no exposure (NE) to AIDS (acquired immunodeficiency syndrome) patients. No HCWs have clinical, serologic, or immunologic evidence of HIV (human immunodeficiency virus) infection. No HCWs in the HE group seroconverted to cytomegalovirus (CMV). One HCW in the HE group seroconverted to Hepatitis B virus (HBV), another HCW in the HE group seroconverted to herpes simplex virus type 2 (HSV-2) although all three groups were similar with respect to HBV and HSV-2 seropositivity. If hospital infection control practices are employed when HCWs care for AIDS patients or work with their biological specimens, the risk of occupationally acquiring a HIV, CMV, HBV or HSV-2 infection appears to be low.
我们对246名女性医护人员进行了为期9至12个月的前瞻性随访，其中102人高暴露于艾滋病（获得性免疫缺陷综合征）患者（高暴露组），43人低暴露于艾滋病患者（低暴露组），101人未暴露于艾滋病患者（无暴露组）。没有医护人员有人类免疫缺陷病毒（HIV）感染的临床、血清学或免疫学证据。高暴露组中没有医护人员巨细胞病毒（CMV）血清学转换。高暴露组中有一名医护人员乙型肝炎病毒（HBV）血清学转换，另一名医护人员2型单纯疱疹病毒（HSV - 2）血清学转换，尽管三组在HBV和HSV - 2血清阳性方面相似。如果医护人员护理艾滋病患者或处理其生物标本时采用医院感染控制措施，职业性感染HIV、CMV、HBV或HSV - 2的风险似乎较低。
