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评估高度近视患者植入可植入式胶原晶状体植入手术前后视网膜血管中的血氧饱和度。

Assessing oxygen saturation in retinal vessels in high myopia patients pre- and post-implantable collamer lens implantation surgery.

作者信息

Chen Pei, Cai Xiaoxiao, Xu Lijun, Zhang Jing, Yang Ying, Gao Qianying, Ge Jian, Yu Keming, Zhuang Jing

机构信息

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

出版信息

Acta Ophthalmol. 2017 Sep;95(6):576-582. doi: 10.1111/aos.13368. Epub 2017 Feb 15.

Abstract

PURPOSE

To determine whether posterior chamber phakic implantable collamer lens (ICL) surgery in high myopia patients impedes oxygen saturation of retinal vessels.

METHODS

Mean oxygen saturation and diameter in retinal blood vessels were measured before and after ICL implantation surgery to correct high myopia refractive errors (i.e. -6.00 to -20.25 dioptres [D]), using an Oxymap T1 retinal oximeter.

RESULTS

In 17 eyes of 17 patients, the Oxymap T1 retinal oximeter detected a small but significant decrease in oxygen saturation of retinal venules, 1-week postoperatively (compared to preoperative measurements). Moreover, at 1 week after ICL implantation, the diameter of patient retinal vessels had consistently contracted, compared to preoperative measurements. By 1 month after ICL surgery, however, both the oxygen saturation and retinal vessel diameter had returned to preoperative levels. Otherwise, no statistically significant difference in oxygen saturation and diameter of retinal arterioles was found when comparing their measurements before and 1 week after implantation.

CONCLUSION

Stable levels of oxygen saturation in retinal vessels, as detected by the Oxymap T1 oximeter, show ICL implantation would not leave lasting impact or adverse effects to retina oxygen saturation in high myopia patients.

摘要

目的

确定高度近视患者后房型有晶体眼可植入式接触镜(ICL)手术是否会影响视网膜血管的氧饱和度。

方法

使用Oxymap T1视网膜血氧仪,在植入ICL手术前后测量视网膜血管的平均氧饱和度和直径,以矫正高度近视屈光不正(即-6.00至-20.25屈光度[D])。

结果

在17例患者的17只眼中,Oxymap T1视网膜血氧仪检测到术后1周视网膜小静脉的氧饱和度有小幅但显著下降(与术前测量相比)。此外,与术前测量相比,ICL植入后1周患者视网膜血管直径持续收缩。然而,ICL手术后1个月,氧饱和度和视网膜血管直径均恢复到术前水平。否则,比较植入前和植入后1周视网膜小动脉的氧饱和度和直径测量值时,未发现统计学上的显著差异。

结论

Oxymap T1血氧仪检测到视网膜血管中的氧饱和度水平稳定,表明ICL植入不会对高度近视患者的视网膜氧饱和度产生持久影响或不良反应。

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