Husein-Elahmed Husein, Gutierrez-Salmeron Maria-Teresa, Aneiros-Cachaza Jose, Naranjo-Sintes Ramon
Department of Dermatology, San Cecilio University Hospital, Granada, Spain.
Department of Pathology, San Cecilio University Hospital, Granada, Spain.
Cutis. 2017 Jan;99(1):55-60.
Basal cell carcinoma (BCC) is the most prevalent malignancy in white individuals and continues to be a serious health problem. Individuals who have sustained exposure to UV radiation are at the highest risk for developing BCC. The aim of this study was to compare the features of BCC in outdoor workers (OWs) with a history of occupational exposure to UV radiation versus indoor workers (IWs). We found that OWs are more likely to develop nodular BCC with no increased risk for superficial BCC. The age of onset of BCC was older in OWs than in IWs. Truncal BCC was more common in IWs, which may suggest other etiological factors are involved in BCC such as genetic predisposition.
基底细胞癌(BCC)是白种人中最常见的恶性肿瘤,并且仍然是一个严重的健康问题。持续暴露于紫外线辐射的个体患基底细胞癌的风险最高。本研究的目的是比较有职业性紫外线辐射暴露史的户外工作者(OWs)与室内工作者(IWs)的基底细胞癌特征。我们发现户外工作者更易患结节性基底细胞癌,而浅表性基底细胞癌的风险没有增加。户外工作者基底细胞癌的发病年龄比室内工作者大。躯干基底细胞癌在室内工作者中更常见,这可能表明基底细胞癌还涉及其他病因,如遗传易感性。