van der Linden M S, Vucic S, van Marrewijk D J F, Ongkosuwito E M
Special Care Dentistry, CBT-Rijnmond, Rotterdam, Netherlands.
Orthodontics, Erasmus MC University Medical Center, Rotterdam, Netherlands.
Orthod Craniofac Res. 2017 May;20(2):65-70. doi: 10.1111/ocr.12139. Epub 2017 Feb 16.
In children with Down syndrome, the timing of dental eruption is important for orthodontics treatment planning. Aim of this study was to determine whether tooth eruption and development of the dentition in children with Down syndrome are impaired.
Dental development was scored on orthopantomograms (OPTs) of 95 children with Down syndrome. The dental age was determined at the left mandibular side according to the Demirjian method and by converting the assigned scores to the dental maturity score. Dental development scores of control children and DS children were compared with a mixed model linear regression analysis.
The model showed statistically significant changes relating to increasing age (P<0.001) and gender (P<0.05). In this comparison, the total DS group (with and without hypodontia) was not statistically significantly different from the control group. There was also no significant difference between the total sample of DS children and the control group after using the Nyström imputation (with and without hypodontia).
The findings showed that dental development in DS children is similar to the development of control children and that a relationship exists between hypodontia and dental development. The clinically observed late eruption is probably not due to late dental development but due to the other processes that take place during eruption, such as the possible impaired processes at the apical side and the occlusal side of an erupting element.
在唐氏综合征患儿中,牙齿萌出时间对于正畸治疗计划很重要。本研究的目的是确定唐氏综合征患儿的牙齿萌出和牙列发育是否受损。
对95名唐氏综合征患儿的口腔全景片(OPT)进行牙齿发育评分。根据德米尔坚方法并将指定分数转换为牙齿成熟度分数,在左下颌侧确定牙龄。通过混合模型线性回归分析比较对照儿童和唐氏综合征患儿的牙齿发育分数。
该模型显示与年龄增长(P<0.001)和性别(P<0.05)相关的统计学显著变化。在该比较中,整个唐氏综合征组(有和无牙缺失)与对照组在统计学上无显著差异。在使用尼斯特伦插补法后(有和无牙缺失),唐氏综合征患儿的总样本与对照组之间也无显著差异。
研究结果表明,唐氏综合征患儿的牙齿发育与对照儿童的发育相似,并且牙缺失与牙齿发育之间存在关联。临床上观察到的萌出延迟可能不是由于牙齿发育延迟,而是由于萌出过程中发生的其他过程,例如正在萌出牙齿的根尖侧和咬合侧可能受损的过程。