Avincsal Mehmet Ozgur, Dinc Mehmet Emre, Ulusoy Seckin, Dalgic Abdullah, Ozdemir Cengiz, Develioglu Omer Necati
*Department of Otorhinolarynology, Gaziosmanpasa Taksim Training and Research Hospital †Sleep Disorders Clinic, Yedikule Chest Disease Education and Research Hospital, Istanbul, Turkey.
J Craniofac Surg. 2017 Jun;28(4):904-908. doi: 10.1097/SCS.0000000000003513.
An accurate, clinical screening tool for obstructive sleep apnea (OSA) that identifies patients for further diagnostic testing would assist in the diagnosis of this comorbidity. One example, the STOP-BANG questionnaire (SBQ), has been validated as a screening tool with high sensitivity. However, its specificity may result in a high false-positive rate. The aim of this study to determine if addition of the Modified Mallampati score to the SBQ improves its specificity.
The authors studied 162 patients referred to the Sleep Disorders Clinic at Yedikule Chest Disease Education and Research Hospital. All patients were prospectively screened for risk of OSA using the SBQ, their oral anatomy was assessed by Modified Mallampati scoring, and sleep quality characterized by polysomnography. Polysomnography results were reviewed when available and the predictive performance of the SBQ and the modified SBQ scoring models were compared.
In the authors' study an SBQ score ≥3 yielded sensitivities of 0.85, 0.86, and 0.91 for Apnea-Hypopnea Index (AHI) ≥5/h, AHI ≥15/h, and AHI ≥30/h, respectively, and specificities of 0.09, 0.10, and 0.18. The modified SBQ with a cutoff of ≥4 (>3) points for AHI levels of >5, >15, and >30 yielded respective sensitivities of 0.84, 0.86, and 0.91 and specificities of 0.25, 0.26, and 0.27.
The author's results from indicated the modified SBQ with a cutoff of >3 points in this study was more specific than the standard SBQ but no less sensitive, and may be used in identifying OSA patients for further diagnostic evaluation or avoiding unnecessary testing.
一种准确的阻塞性睡眠呼吸暂停(OSA)临床筛查工具,用于识别需要进一步诊断测试的患者,将有助于诊断这种合并症。一个例子是STOP-BANG问卷(SBQ),它已被验证为具有高灵敏度的筛查工具。然而,其特异性可能导致高假阳性率。本研究的目的是确定在SBQ中加入改良的马兰帕蒂评分是否能提高其特异性。
作者研究了162名转诊至耶迪库勒胸科疾病教育与研究医院睡眠障碍诊所的患者。所有患者均使用SBQ进行OSA风险的前瞻性筛查,通过改良的马兰帕蒂评分评估其口腔解剖结构,并通过多导睡眠图对睡眠质量进行表征。如有可用的多导睡眠图结果,则进行回顾,并比较SBQ和改良SBQ评分模型的预测性能。
在作者的研究中,SBQ评分≥3时,对于呼吸暂停低通气指数(AHI)≥5次/小时、AHI≥15次/小时和AHI≥30次/小时,灵敏度分别为0.85、0.86和0.91,特异性分别为0.09、0.10和0.18。对于AHI水平>5、>15和>30,改良SBQ的截断值≥4(>3)分时,灵敏度分别为0.84、0.86和0.91,特异性分别为0.25、0.26和0.27。
作者的结果表明,本研究中截断值>3分以上的改良SBQ比标准SBQ更具特异性,但灵敏度不低,可用于识别OSA患者以进行进一步的诊断评估或避免不必要的检测。