Bruze Gustaf, Ottosson Johan, Neovius Martin, Näslund Ingmar, Marsk Richard
Department of Medicine, Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.
Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Surg Obes Relat Dis. 2017 Jun;13(6):962-969. doi: 10.1016/j.soard.2017.01.004. Epub 2017 Jan 5.
Several studies have addressed short-term admission rates after bariatric surgery. However, studies on long-term admission rates are few and population based studies are even scarcer.
The aim of this study was to assess short- and long-term admission rates for gastrointestinal surgery after gastric bypass in Sweden compared with admission rates in the general population.
Swedish healthcare system.
The surgery cohort consisted of adults with body mass index≥35 identified in the Scandinavian Obesity Surgery Registry (n = 28,331; mean age 41 years; 76% women; Roux-en-Y gastric bypass performed 2007-2012). For each individual, up to 10 comparators from the general population were matched on birth year, sex, and place of residence (n = 274,513). The primary outcome was inpatient admissions due to gastrointestinal surgery retrieved from the National Patient Register through December 31, 2014. Conditional hazard ratios (HR) were estimated using Cox regression.
All-cause admission rates were 6.5%, 21.4%, and 65.9% during 30 days, 1 year, and 6 years after surgery, respectively. The corresponding rates for gastrointestinal surgery were 1.8%, 6.8%, and 24.4%. Compared with that of the general population, there was an increased risk of all-cause hospital admission at 1 year (HR 2.6 [2.5-2.6]) and 6 years (HR 2.7 [2.6-2.7]). The risk of hospital admission for any gastrointestinal surgical procedure was greatly increased throughout the study period (HR 8.6 [8.4-8.9]). Female sex, psychiatric disease, and low education were risk factors.
We found a significant risk of admission to hospital over>6 years after gastric bypass surgery.
多项研究探讨了减肥手术后的短期住院率。然而,关于长期住院率的研究较少,基于人群的研究更为罕见。
本研究旨在评估瑞典胃旁路术后胃肠道手术的短期和长期住院率,并与普通人群的住院率进行比较。
瑞典医疗保健系统。
手术队列包括在斯堪的纳维亚肥胖手术登记处确定的体重指数≥35的成年人(n = 28,331;平均年龄41岁;76%为女性;2007 - 2012年进行Roux - en - Y胃旁路手术)。为每个个体,在出生年份、性别和居住地点方面匹配多达10名普通人群的对照者(n = 274,513)。主要结局是截至2014年12月31日从国家患者登记处检索到的因胃肠道手术的住院情况。使用Cox回归估计条件风险比(HR)。
术后30天、1年和6年的全因住院率分别为6.5%、21.4%和65.9%。胃肠道手术的相应比率分别为1.8%、6.8%和24.4%。与普通人群相比,1年(HR 2.6 [2.5 - 2.6])和6年(HR 2.7 [2.6 - 2.7])时全因住院风险增加。在整个研究期间,任何胃肠道手术的住院风险均大幅增加(HR 8.6 [8.4 - 8.9])。女性、精神疾病和低教育程度是风险因素。
我们发现胃旁路手术后6年以上有显著的住院风险。