Sestieri Carlo, Shulman Gordon L, Corbetta Maurizio
Department of Neuroscience, Imaging and Clinical Sciences, Institute of Advanced Biomedical Technologies, University of Chieti, 66100 Chieti, Italy.
Department of Neurology, Washington University School of Medicine St. Louis, Missouri 63110, USA.
Nat Rev Neurosci. 2017 Feb 17;18(3):183-192. doi: 10.1038/nrn.2017.6.
The posterior parietal cortex (PPC) is traditionally associated with attention, perceptual decision making and sensorimotor transformations, but more recent human neuroimaging studies support an additional role in episodic memory retrieval. In this Opinion article, we present a functional-anatomical model of the involvement of the PPC in memory retrieval. Parietal regions involved in perceptual attention and episodic memory are largely segregated and often show a push-pull relationship, potentially mediated by prefrontal regions. Moreover, different PPC regions carry out specific functions during retrieval - for example, representing retrieved information, recoding this information based on task demands, or accumulating evidence for memory decisions.
传统上,顶叶后皮质(PPC)与注意力、知觉决策和感觉运动转换相关,但最近的人类神经影像学研究支持其在情景记忆检索中发挥额外作用。在这篇观点文章中,我们提出了一个关于PPC参与记忆检索的功能解剖模型。参与知觉注意力和情景记忆的顶叶区域在很大程度上是分开的,并且经常呈现出一种推拉关系,这可能由前额叶区域介导。此外,不同的PPC区域在检索过程中执行特定功能——例如,表征检索到的信息,根据任务需求对该信息进行重新编码,或为记忆决策积累证据。