膜翅目昆虫毒液过敏的关键问题：最新进展

Key Issues in Hymenoptera Venom Allergy: An Update.

作者信息

Alfaya Arias T, Soriano Gómis V, Soto Mera T, Vega Castro A, Vega Gutiérrez J M, Alonso Llamazares A, Antolín Amérigo D, Carballada Gonzalez F J, Dominguez Noche C, Gutierrez Fernandez D, Marques Amat L, Martinez Arcediano A, Martinez San Ireneo M, Moreno Ancillo A, Puente Crespo Y, Ruiz Leon B, Sánchez Morillas L

机构信息

Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.

Hospital General Universitario de Alicante, Alicante, Spain.

出版信息

J Investig Allergol Clin Immunol. 2017;27(1):19-31. doi: 10.18176/jiaci.0123.

DOI:10.18176/jiaci.0123

PMID:28211342

Abstract

In this review, the Hymenoptera Allergy Committee of the SEAIC analyzes the most recent scientific literature addressing problems related to the diagnosis of hymenoptera allergy and to management of venom immunotherapy. Molecular diagnosis and molecular risk profiles are the key areas addressed. The appearance of new species of hymenoptera that are potentially allergenic in Spain and the associated diagnostic and therapeutic problems are also described. Finally, we analyze the issue of mast cell activation syndrome closely related to hymenoptera allergy, which has become a new diagnostic challenge for allergists given its high prevalence in patients with venom anaphylaxis.

摘要

在本综述中，西班牙变态反应、免疫和临床免疫学会膜翅目过敏委员会分析了关于膜翅目过敏诊断及毒液免疫治疗管理相关问题的最新科学文献。分子诊断和分子风险概况是重点探讨的领域。文中还描述了在西班牙可能具有致敏性的新膜翅目物种的出现情况以及相关的诊断和治疗问题。最后，我们分析了与膜翅目过敏密切相关的肥大细胞活化综合征问题，鉴于其在毒液过敏反应患者中的高患病率，这已成为过敏症专科医生面临的一项新的诊断挑战。