Davila Jessica A, Hartman Christine, Cully Jeffrey, Stanley Melinda, Amico K Rivet, Soriano Elizabeth, Minick Sophie, May Sarah B, Giordano Thomas P
a VA Health Services Research Center of Excellence, Michael E. DeBakey Veterans Affairs Medical Center , Houston , TX , USA.
b Department of Medicine , Sections of Health Services Research , Baylor College of Medicine , Houston , TX , USA.
HIV Clin Trials. 2017 Mar;18(2):75-82. doi: 10.1080/15284336.2017.1287536. Epub 2017 Feb 17.
The hospital setting provides an opportunity to re-engage people living with HIV (PLWH) in HIV care. We developed and implemented a protocol to identify PLWH in a hospital setting. The aim of the current study was to report on our strategy to recruit hospitalized HIV patients into an intervention study, and to report on lessons learned for future studies.
Our protocol was developed based on experience of our research staff in recruiting HIV patients as well as clinical input from providers and administrators on delivering care in hospitalized settings. We identified hospitalized PLWH between 2010 and 2013 who were potentially eligible for an intervention study. Patients were identified by review of electronic medical records and clinician referral, followed by in-person screening to confirm eligibility. We examined factors related to identifying and enrolling hospitalized patients, and documented lessons learned.
Key strategies included systematic medical record review followed by in-person screening, collaboration with staff, and flexibility in recruitment logistics. We identified 1801 PLWH hospitalized during the 3-year study period. Eighty-four percent (n = 1514) met the met the inclusion criteria based on medical record review. Of these, 48% (n = 733) were ineligible. Among eligible patients, 59% (n = 460) were enrolled. Only 3% (n = 23) of eligible patients declined; 84% (n = 321) were not enrolled because they were discharged before enrollment. Lessons learned included (1) needing to identify patients and deliver the intervention before hospital discharge, (2) limiting the complexity of the intervention, and (3) having research staff available on weekends and after hours.
Targeted recruitment of hospitalized populations is a feasible and productive approach for finding and engaging PLWH who are newly diagnosed or out of routine care.
医院环境为促使艾滋病毒感染者(PLWH)重新接受艾滋病毒治疗提供了契机。我们制定并实施了一项在医院环境中识别PLWH的方案。本研究的目的是报告我们将住院艾滋病毒患者纳入一项干预研究的策略,并报告从中学到的经验教训,供未来研究参考。
我们的方案是基于研究人员招募艾滋病毒患者的经验以及医疗服务提供者和管理人员在医院环境中提供护理的临床意见而制定的。我们确定了2010年至2013年间住院的可能符合干预研究条件的PLWH。通过查阅电子病历和临床医生转诊来识别患者,随后进行面对面筛查以确认其符合条件。我们研究了与识别和招募住院患者相关的因素,并记录了学到的经验教训。
关键策略包括系统的病历审查,随后进行面对面筛查、与工作人员合作以及在招募后勤方面保持灵活性。在为期3年的研究期间,我们识别出1801名住院的PLWH。根据病历审查,84%(n = 1514)符合纳入标准。其中,48%(n = 733)不符合条件。在符合条件的患者中,59%(n = 460)被纳入研究。只有3%(n = 23)的符合条件患者拒绝参与;84%(n = 321)未被纳入是因为他们在登记前已出院。学到的经验教训包括:(1)需要在患者出院前识别并实施干预;(2)限制干预的复杂性;(3)在周末和非工作时间安排研究人员值班。
针对性地招募住院人群是一种可行且有效的方法,有助于找到并促使新诊断或脱离常规护理的PLWH参与治疗。