用于预测和建模具有生物学意义蛋白质的ProBiS工具（算法、数据库和网络服务器）。
ProBiS tools (algorithm, database, and web servers) for predicting and modeling of biologically interesting proteins.
作者信息
Konc Janez, Janežič Dušanka
机构信息
National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia; Faculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Glagoljaška 8, SI-6000, Koper, Slovenia.
Faculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Glagoljaška 8, SI-6000, Koper, Slovenia.
出版信息
Prog Biophys Mol Biol. 2017 Sep;128:24-32. doi: 10.1016/j.pbiomolbio.2017.02.005. Epub 2017 Feb 15.
ProBiS (Protein Binding Sites) Tools consist of algorithm, database, and web servers for prediction of binding sites and protein ligands based on the detection of structurally similar binding sites in the Protein Data Bank. In this article, we review the operations that ProBiS Tools perform, provide comments on the evolution of the tools, and give some implementation details. We review some of its applications to biologically interesting proteins. ProBiS Tools are freely available at http://probis.cmm.ki.si and http://probis.nih.gov.
ProBiS（蛋白质结合位点）工具由算法、数据库和网络服务器组成，用于基于蛋白质数据库中结构相似结合位点的检测来预测结合位点和蛋白质配体。在本文中，我们回顾了ProBiS工具所执行的操作，对这些工具的发展进行了评论，并给出了一些实现细节。我们还回顾了其在一些具有生物学意义的蛋白质上的应用。ProBiS工具可在http://probis.cmm.ki.si和http://probis.nih.gov免费获取。
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