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聚二氧六环酮、聚乙醇酸和肠线缝合线在无菌和感染尿液中的性能体外比较

In vitro comparison of the properties of polydioxanone, polyglycolic acid and catgut sutures in sterile and infected urine.

作者信息

el-Mahrouky A, McElhaney J, Bartone F F, King L

机构信息

Division of Urology, Duke University, Durham, North Carolina.

出版信息

J Urol. 1987 Oct;138(4):913-5. doi: 10.1016/s0022-5347(17)43415-x.

Abstract

The effect of immersion in sterile urine, infected urine and plasma on the breaking strength and stiffness of polydioxanone (PDS), polyglycolic acid (PGA) and chromic catgut was studied. Tests were done under closely controlled conditions with immersion periods varying from zero to ten days. The breaking strength and stiffness of the three suture materials was not significantly changed by immersion in plasma for periods up to ten days. In sterile urine, PDS lost all of its strength after three days of immersion while PGA lost 64% of its initial breaking strength after ten days. Catgut maintained its strength over the ten day study period. In E. coli-infected urine, PDS lost all of its strength in six days while PGA lost 71% and catgut 8% after ten days. In proteus-infected urine, PDS and PGA lost all their breaking strength after one day of immersion while catgut lost 5.8% of its initial strength after 10 days. Corresponding decreases in stiffness were also observed.

摘要

研究了将聚二氧六环酮(PDS)、聚乙醇酸(PGA)和铬制肠线浸泡在无菌尿液、感染尿液和血浆中对其断裂强度和硬度的影响。试验在严格控制的条件下进行,浸泡时间从0天到10天不等。三种缝合材料浸泡在血浆中长达10天,其断裂强度和硬度没有显著变化。在无菌尿液中,PDS浸泡三天后失去了所有强度,而PGA浸泡十天后失去了其初始断裂强度的64%。肠线在十天的研究期内保持了其强度。在大肠杆菌感染的尿液中,PDS在六天内失去了所有强度,而PGA在十天后失去了71%,肠线失去了8%。在变形杆菌感染的尿液中,PDS和PGA浸泡一天后失去了所有断裂强度,而肠线在10天后失去了其初始强度的5.8%。还观察到了相应的硬度下降。

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