Bartone F, Shore N, Newland J, King L, DuPlessis D
Urology. 1987 May;29(5):517-22. doi: 10.1016/0090-4295(87)90042-2.
In a study designed to determine the best suture for use in hypospadias surgery, polydioxanone (PDS), chromic catgut, and polyglycolic acid (Dexon) were studied under similar conditions in the penile foreskin of 16 baboons. Gross and microscopic observations were made at intervals of six to forty-eight days. The wounds sutured with catgut were all healed by twenty-four days with complete suture resorption and no evidence of scar formation. Both polyglycolic acid and polydioxanone sutures showed delayed resorption, wound abscesses, and granulomas. Catgut remains the best available suture to use in the penile foreskin. Polyglycolic acid and polydioxanone sutures, because of their prolonged resorption and excess reaction, should not be used in hypospadias surgery.
在一项旨在确定用于尿道下裂手术的最佳缝线的研究中，在16只狒狒的阴茎包皮上，于相似条件下对聚二氧六环酮（PDS）、铬制肠线和聚乙醇酸（德克松）进行了研究。在6至48天的间隔时间进行大体和显微镜观察。用肠线缝合的伤口在24天时全部愈合，缝线完全吸收，且无瘢痕形成迹象。聚乙醇酸和聚二氧六环酮缝线均显示出吸收延迟、伤口脓肿和肉芽肿。肠线仍是阴茎包皮手术中可用的最佳缝线。聚乙醇酸和聚二氧六环酮缝线由于吸收时间延长和过度反应，不应在尿道下裂手术中使用。
