Chang Po-Chih, Huang Chih-Kun, Tai Chi-Ming, Huang Ivy Ya-Wei, Hsin Ming-Che, Hung Chao-Ming
Bariatric and Metabolic International Surgery Center, E-Da Hospital, I-Shou University, Kaohsiung City, Taiwan; Division of Thoracic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan; Weight Management Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan; Department of Sports Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan.
Body Science and Metabolic Disorders International Medical Center, China Medical University Hospital, Taichung City, Taiwan.
Surg Obes Relat Dis. 2017 Apr;13(4):588-593. doi: 10.1016/j.soard.2016.09.035. Epub 2016 Oct 4.
Marginal ulcer (MU) is not infrequent after laparoscopic Roux-en-Y gastric bypass (LRYGB). Medication plus lifestyle modification remains the mainstay solution. Patients with refractory MU may be candidates for revisional surgery.
To summarize our experience of revisional surgery for treating refractory MU after LRYGB.
University hospital, Taiwan.
A retrospective analysis was performed for 11 patients with refractory MU undergoing totally hand-sewn gastrojejunostomy and truncal vagotomy at our institution between August 2005 and May 2015. The mean follow-up after surgery was 28.0±16.2 months (range, 10-48 mo); 9 patients (81.8%) were followed up more than 1 year after.
The mean age of the cohort (7 males; 4 females) was 39.5±16.0 years (range, 19-66 yr), with a mean initial body mass index of 37.5±9.3 kg/m (range, 32.1-57 kg/m). Intractability was the dominant manifestation (100%); 8 patients (72%) had stricture at the gastrojejunostomy. The mean interval from initial LRYGB to refractory MU and revisional surgery was 10.2±7.7 months (range, 4-28 mo) and 38.7±21.6 months (range, 10-67 mo), respectively. The average operation time was 150.4±59.8 minutes (range, 80-300 min), and the average length of hospital stay was 4.2±1.4 days (range, 2-7 d). The 9 patients with more than 1 year follow-up all achieved endoscopic resolution of the refractory MU.
Although longer follow-up is warranted, revisional surgery with totally hand-sewn gastrojejunostomy and truncal vagotomy can be an effective solution for refractory MU.
腹腔镜Roux-en-Y胃旁路术(LRYGB)后边缘性溃疡(MU)并不少见。药物治疗加生活方式改变仍是主要的解决方法。难治性MU患者可能适合进行翻修手术。
总结我们治疗LRYGB术后难治性MU的翻修手术经验。
台湾的大学医院。
对2005年8月至2015年5月在我院接受全手工缝合胃空肠吻合术和迷走神经干切断术的11例难治性MU患者进行回顾性分析。术后平均随访时间为28.0±16.2个月(范围10 - 48个月);9例患者(81.8%)随访时间超过1年。
该队列(7例男性;4例女性)的平均年龄为39.5±16.0岁(范围19 - 66岁),初始平均体重指数为37.5±9.3kg/m²(范围32.1 - 57kg/m²)。难治性是主要表现(100%);8例患者(72%)胃空肠吻合口有狭窄。从初次LRYGB到难治性MU和翻修手术的平均间隔时间分别为10.2±7.7个月(范围4 - 28个月)和38.7±21.6个月(范围10 - 67个月)。平均手术时间为150.4±59.8分钟(范围80 - 300分钟),平均住院时间为4.2±1.4天(范围2 - 7天)。9例随访超过1年的患者难治性MU均在内镜下得到缓解。
尽管需要更长时间的随访,但全手工缝合胃空肠吻合术和迷走神经干切断术的翻修手术可能是治疗难治性MU的有效方法。