Chau Edward, Youn Heekoung, Ren-Fielding Christine J, Fielding George A, Schwack Bradley F, Kurian Marina S
Department of Surgery, NYU School of Medicine, New York, New York.
Department of Surgery, NYU School of Medicine, New York, New York.
Surg Obes Relat Dis. 2015 Sep-Oct;11(5):1071-5. doi: 10.1016/j.soard.2014.12.011. Epub 2014 Dec 19.
Marginal ulcers (MUs) are potentially complex complications after Roux-en-Y gastric bypass. Although most resolve with medical management, some require surgical intervention. Many surgical options exist, but there is no standardized approach, and few reports of outcomes have been documented in the literature. The objective of this study was to determine the outcomes of surgical management of marginal ulcers.
Data from all patients who underwent surgical intervention between 2004 and 2012 for treatment of MU after previous Roux-en-Y gastric bypass were reviewed.
Twelve patients with MUs underwent reoperation. Nine patients had associated gastrogastric fistulae (75%). The median time to reoperation was 43 months. Ten patients underwent subtotal gastrectomy, of which 9 had a revision of the gastrojejunal anastomosis and 1 did not. One underwent total gastrectomy with esophagojejunal anastomosis for ulcer after previous revisional partial gastrectomy, and 1 patient underwent video-assisted thoracoscopic truncal vagotomy for persistent ulcer-related bleeding in the early postoperative period. Three patients (25%) experienced postoperative complications associated with revisional surgery requiring reoperation. At median follow-up time of 35 months, 7 patients (58%) had chronic abdominal pain, and 4 patients (33%) had intermittent diarrhea. Three patients (25%) were lost to recent follow-up. None had recurrence of MU.
Patients can undergo one of several available surgical interventions, including laparoscopic subtotal gastrectomy with gastrojejunostomy revision. Though this appears to offer definitive treatment of MU, its benefits must be weighed against the increased risk of significant postoperative complications and chronic symptoms related to revisional surgery.
边缘性溃疡(MU)是Roux-en-Y胃旁路术后潜在的复杂并发症。尽管大多数通过药物治疗可缓解,但有些需要手术干预。存在多种手术选择,但没有标准化方法,且文献中记录的结局报告很少。本研究的目的是确定边缘性溃疡手术治疗的结局。
回顾了2004年至2012年间所有因先前Roux-en-Y胃旁路术后的MU而接受手术干预的患者的数据。
12例MU患者接受了再次手术。9例患者伴有胃胃瘘(75%)。再次手术的中位时间为43个月。10例患者接受了胃次全切除术,其中9例进行了胃空肠吻合术修复,1例未进行。1例在先前的部分胃切除术后因溃疡接受了食管空肠吻合术的全胃切除术,1例患者在术后早期因持续性溃疡相关出血接受了电视辅助胸腔镜迷走神经干切断术。3例患者(25%)经历了与再次手术相关的术后并发症,需要再次手术。在中位随访时间35个月时,7例患者(58%)有慢性腹痛,4例患者(33%)有间歇性腹泻。3例患者(25%)失访。均无MU复发。
患者可接受几种可用的手术干预之一,包括腹腔镜胃次全切除术并修复胃空肠吻合术。虽然这似乎能为MU提供确定性治疗,但其益处必须与术后严重并发症和再次手术相关慢性症状的风险增加相权衡。