Bocharov Andrey V, Knyazev Gennady G, Savostyanov Alexander N
Federal State Budgetary Scientific Institution "Scientific Research Institute of Physiology and Basic Medicine", Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia.
Federal State Budgetary Scientific Institution "Scientific Research Institute of Physiology and Basic Medicine", Novosibirsk, Russia.
Neurophysiol Clin. 2017 Jun;47(3):225-230. doi: 10.1016/j.neucli.2017.01.009. Epub 2017 Feb 16.
Depression is one of the most prevalent mental illnesses and is associated with changes in emotion processing. The aim of this study was to determine the influence of depressive symptoms on EEG oscillatory dynamics accompanying implicit processing of angry and happy facial expressions in 46 healthy subjects.
The Beck Depression Inventory was used to assess the presence of depressive symptoms in normal subjects. During the experiment, they were told to categorize the gender of angry, neutral, or happy faces presented to them, while high-resolution EEG was recorded. Analysis of the event-related spectral perturbations and the analysis of dipoles were carried out on EEG recordings using the EEGLAB toolbox.
High depression (HD) and low depression (LD) groups did not differ on error rate and reaction time during categorization of gender. The perception of happy faces was accompanied by higher theta synchronization in the LD than the HD group. In contrast, theta synchronization was higher in the HD than the LD group during perception of angry faces.
These findings imply that even at preclinical stages, HD scorers evidence increased emotional arousal to negative and decreased emotional arousal to positive stimuli during implicit emotion processing.
抑郁症是最常见的精神疾病之一，与情绪加工的变化有关。本研究的目的是确定46名健康受试者在对愤怒和快乐面部表情进行内隐加工时，抑郁症状对脑电图振荡动力学产生的影响。
使用贝克抑郁量表评估正常受试者抑郁症状的存在情况。在实验过程中，要求他们对呈现给他们的愤怒、中性或快乐面孔的性别进行分类，同时记录高分辨率脑电图。使用EEGLAB工具箱对脑电图记录进行事件相关频谱扰动分析和偶极子分析。
在性别分类过程中，高抑郁（HD）组和低抑郁（LD）组在错误率和反应时间上没有差异。与HD组相比，LD组在感知快乐面孔时伴随着更高的θ波同步化。相反，在感知愤怒面孔时，HD组的θ波同步化高于LD组。
这些发现表明，即使在临床前阶段，HD评分者在情绪内隐加工过程中也表现出对负面刺激的情绪唤醒增加，对正面刺激的情绪唤醒减少。
