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宫颈旁阻滞对子宫输卵管造影术女性患者镇痛的有效性。

Effectiveness of paracervical block for pain relief in women undergoing hysterosalpingography.

作者信息

Jain Shikha, Inamdar Dattaprasad B, Majumdar Abha, Jain Deepak K

机构信息

Centre of IVF and Human Reproduction, Sir Ganga Ram Hospital, New Delhi, India.

Senior Resident, Department of Surgical Oncology, TATA Memorial Hospital, Mumbai, Maharashtra, India.

出版信息

J Hum Reprod Sci. 2016 Oct-Dec;9(4):230-235. doi: 10.4103/0974-1208.197643.

DOI:10.4103/0974-1208.197643
PMID:28216910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5296826/
Abstract

OBJECTIVES

To evaluate the potential benefit, in terms of pain relief, of the paracervical block with 2% lignocaine in women undergoing hysterosalpingography (HSG).

STUDY DESIGN

This study was a prospective randomized controlled study.

SETTINGS

This study was conducted in infertility clinic of a tertiary care center.

MATERIALS AND METHODS

Four hundred and six patients undergoing HSG as a part of infertility evaluation were included in the study. These women were randomized into two groups: Group I received paracervical block with 2% lignocaine at the time of HSG ( = 53) and Group II ( = 53) served as control. Hyoscine (10 mg) oral tablet was given to all the patients 30 min before the procedure. Pain perception during the procedure was analyzed by the patient between 0 and 10 on a numeric rating scale, immediately after HSG.

RESULTS

The baseline demographic characteristics of participants in two groups were similar. Mean pain score immediately after HSG in the study group and control group was 4.84 ± 2.56 and 5.21 ± 1.89, respectively ( = 0.21).

CONCLUSIONS

There is no benefit of paracervical block with 2% lignocaine, in terms of pain relief, in women undergoing HSG.

摘要

目的

评估在子宫输卵管造影术(HSG)中使用2%利多卡因宫颈旁阻滞在缓解疼痛方面的潜在益处。

研究设计

本研究为前瞻性随机对照研究。

研究地点

本研究在一家三级医疗中心的不孕不育诊所进行。

材料与方法

406名接受HSG作为不孕不育评估一部分的患者纳入研究。这些女性被随机分为两组:第一组在HSG时接受2%利多卡因宫颈旁阻滞(n = 203),第二组(n = 203)作为对照组。所有患者在操作前30分钟口服10毫克东莨菪碱片剂。操作过程中的疼痛感知由患者在HSG后立即用数字评分量表从0到10进行分析。

结果

两组参与者的基线人口统计学特征相似。研究组和对照组在HSG后立即的平均疼痛评分分别为4.84±2.56和5.21±1.89(P = 0.21)。

结论

在接受HSG的女性中,使用2%利多卡因宫颈旁阻滞在缓解疼痛方面没有益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/305e03bd4568/JHRS-9-230-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/c091f5889f5d/JHRS-9-230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/bbad7374e4ae/JHRS-9-230-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/305e03bd4568/JHRS-9-230-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/c091f5889f5d/JHRS-9-230-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/bbad7374e4ae/JHRS-9-230-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a47/5296826/305e03bd4568/JHRS-9-230-g003.jpg

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本文引用的文献

1
Pain relief in hysterosalpingography.子宫输卵管造影术中的疼痛缓解。
Cochrane Database Syst Rev. 2015 Sep 20;2015(9):CD006106. doi: 10.1002/14651858.CD006106.pub3.
2
Comparison of four different pain relief methods during hysterosalpingography: a randomized controlled study.子宫输卵管造影术中四种不同疼痛缓解方法的比较:一项随机对照研究。
Pain Res Manag. 2015 Mar-Apr;20(2):107-11. doi: 10.1155/2015/306248.
3
Can the addition of a paracervical block to systemic or local analgesics improve the pain perceived by the patient during hysterosalpingography?
在全身或局部镇痛药基础上加用宫颈旁阻滞能否减轻患者在子宫输卵管造影术中的疼痛?
J Obstet Gynaecol. 2014 Jan;34(1):48-53. doi: 10.3109/01443615.2013.828025.
4
Paracervical local anaesthesia for cervical dilatation and uterine intervention.用于宫颈扩张和子宫干预的宫颈旁局部麻醉。
Cochrane Database Syst Rev. 2013 Sep 30(9):CD005056. doi: 10.1002/14651858.CD005056.pub3.
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Definitions of infertility and recurrent pregnancy loss: a committee opinion.不孕和复发性流产的定义:委员会意见。
Fertil Steril. 2013 Jan;99(1):63. doi: 10.1016/j.fertnstert.2012.09.023. Epub 2012 Oct 22.
6
Pain relief during hysterosalpingography: role of intracervical block.子宫输卵管造影术中的止痛:宫颈阻滞的作用。
Arch Gynecol Obstet. 2013 Jan;287(1):155-9. doi: 10.1007/s00404-012-2515-z. Epub 2012 Aug 28.
7
Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP).成人疼痛测量方法:疼痛视觉模拟量表(VAS疼痛)、疼痛数字评定量表(NRS疼痛)、麦吉尔疼痛问卷(MPQ)、简化麦吉尔疼痛问卷(SF-MPQ)、慢性疼痛分级量表(CPGS)、简短健康调查36项身体疼痛量表(SF-36 BPS)以及间歇性和持续性骨关节炎疼痛测量量表(ICOAP)。
Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S240-52. doi: 10.1002/acr.20543.
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Strategies to minimize discomfort during diagnostic hysterosalpingography with disposable balloon catheters: a randomized placebo-controlled study with oral nonsteroidal premedication.使用一次性球囊导管在诊断性子宫输卵管造影术中减轻不适的策略:一项口服非甾体类药物预处理的随机安慰剂对照研究。
Fertil Steril. 2008 Sep;90(3):844-8. doi: 10.1016/j.fertnstert.2007.07.1302. Epub 2007 Oct 22.
9
Lidocaine-prilocaine (EMLA) cream as analgesia for hysterosalpingography: a prospective, randomized, controlled, double blinded study.利多卡因-丙胺卡因(EMLA)乳膏用于子宫输卵管造影术的镇痛:一项前瞻性、随机、对照、双盲研究。
Hum Reprod. 2007 May;22(5):1335-9. doi: 10.1093/humrep/del517. Epub 2007 Jan 18.
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Obstet Gynecol. 2007 Jan;109(1):89-93. doi: 10.1097/01.AOG.0000247645.52211.41.