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哌甲酯诱发的强迫症状:一例报告及文献综述

Methylphenidate-induced obsessive-compulsive symptoms: A case report and review of literature.

作者信息

Jhanda Soumya, Singla Neha, Grover Sandeep

机构信息

Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J Pediatr Neurosci. 2016 Oct-Dec;11(4):316-318. doi: 10.4103/1817-1745.199461.

Abstract

Literature on the association of methylphenidate and obsessive-compulsive symptoms (OCS) is sparse. This report discusses a case of a 14-year-old boy, who developed OCS (in the form of need for symmetry, obsessive doubts; compulsive symptoms included the need to order/arrange articles and repeated checking behavior), within 10 days of starting methylphenidate at the dose of 15 mg/day. Stoppage of methylphenidate led to amelioration of OCS over 2 weeks. The case description suggests that whenever a child on stimulants presents with new-onset OCS, association of OCS with stimulants must be suspected before considering an independent diagnosis of comorbid OCS/obsessive-compulsive disorder.

摘要

关于哌甲酯与强迫症状(OCS)关联的文献稀少。本报告讨论了一名14岁男孩的病例,该男孩在开始服用15毫克/天剂量的哌甲酯后10天内出现了OCS(表现为对对称性的需求、强迫性怀疑;强迫症状包括对物品进行整理/排列的需求以及反复检查行为)。停用哌甲酯后,OCS在2周内得到改善。该病例描述表明,每当服用兴奋剂的儿童出现新发OCS时,在考虑独立诊断为共病OCS/强迫症之前,必须怀疑OCS与兴奋剂之间存在关联。

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本文引用的文献

3
Dexamphetamine for obsessive-compulsive disorder.
Am J Psychiatry. 2003 Jan;160(1):183. doi: 10.1176/appi.ajp.160.1.183.
6
Methylphenidate-induced obsessive-compulsiveness.
J Am Acad Child Adolesc Psychiatry. 1998 Feb;37(2):135. doi: 10.1097/00004583-199802000-00001.
7
Obsessive-compulsive symptoms following stimulants.兴奋剂使用后的强迫症状。
Biol Psychiatry. 1985 Dec;20(12):1332-3. doi: 10.1016/0006-3223(85)90120-9.

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