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孕期宫颈弹性成像测量:现状与未来挑战

Elastographic measurement of the cervix during pregnancy: Current status and future challenges.

作者信息

Kim Hyunjung, Hwang Han Sung

机构信息

Department of Obstetrics and Gynecology, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea.

出版信息

Obstet Gynecol Sci. 2017 Jan;60(1):1-7. doi: 10.5468/ogs.2017.60.1.1. Epub 2017 Jan 19.

DOI:10.5468/ogs.2017.60.1.1
PMID:28217665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5313350/
Abstract

The cervix is a cylindrical structure that is proximally connected to the uterus and distally to the vaginal cavity. The Bishop score has been used to evaluate the cervix during pregnancy. However, alternatives have been evaluated because the Bishop score is uncomfortable for patients, relies on a subjective examination, and lacks internal os data. Elastography has been used to assess the cervix, as it can estimate tissue stiffness. Recent articles on elastography for cervical assessment during pregnancy have focused on its usefulness for prediction of preterm birth and successful labor induction. There is a clinical need for cervical elastography, as an evaluation of biomechanical factors, because cervical length only assesses morphological changes. However, until now, cervical elastography has been studied in the limited field, and not shown a uniformed methodological technique. In this review, the current status, limitations, and future possibility of cervical elastography were discussed. Future studies should focus on overcoming the limitations of cervical elastography. Although the cervical elastography is presently an incompletely defined technique, it needs to be improved and evaluated as a method for use in combination with cervical length.

摘要

子宫颈是一个圆柱形结构,近端连接子宫,远端连接阴道腔。Bishop评分一直用于评估孕期的子宫颈。然而,由于Bishop评分让患者不适、依赖主观检查且缺乏宫颈内口数据,人们已经对其他方法进行了评估。弹性成像已被用于评估子宫颈,因为它可以估计组织硬度。最近关于孕期子宫颈弹性成像评估的文章主要关注其对早产预测和引产成功的有用性。作为生物力学因素的评估方法,子宫颈弹性成像在临床上是有需求的,因为宫颈长度仅评估形态学变化。然而,到目前为止,子宫颈弹性成像仅在有限的领域进行了研究,尚未显示出统一的方法技术。在本综述中,讨论了子宫颈弹性成像的现状、局限性和未来可能性。未来的研究应专注于克服子宫颈弹性成像的局限性。尽管目前子宫颈弹性成像是一种定义不完整的技术,但它需要作为一种与宫颈长度联合使用的方法进行改进和评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/9c4a751d7823/ogs-60-1-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/24d37ee347ef/ogs-60-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/5298246578e5/ogs-60-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/9c4a751d7823/ogs-60-1-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/24d37ee347ef/ogs-60-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/5298246578e5/ogs-60-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c0d/5313350/9c4a751d7823/ogs-60-1-g003.jpg

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The utility of combined utero-cervical ındex in predicting preterm delivery in pregnant women with preterm uterine contractions.联合子宫颈指数在预测有早产宫缩的孕妇早产中的效用。
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本文引用的文献

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JSUM ultrasound elastography practice guidelines: breast.JSUM超声弹性成像实践指南:乳腺
J Med Ultrason (2001). 2013 Oct;40(4):359-91. doi: 10.1007/s10396-013-0457-0. Epub 2013 Jul 31.
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JSUM ultrasound elastography practice guidelines: liver.JSUM超声弹性成像实践指南:肝脏
J Med Ultrason (2001). 2013 Oct;40(4):325-57. doi: 10.1007/s10396-013-0460-5. Epub 2013 Aug 16.
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A universal mid-trimester transvaginal cervical length screening program and its associated reduced preterm birth rate.普遍的中期经阴道宫颈长度筛查方案及其相关的早产率降低。
预测单胎妊娠且宫颈短且无自发性早产史的自发性早产的列线图的开发与验证
Heliyon. 2023 Sep 27;9(10):e20453. doi: 10.1016/j.heliyon.2023.e20453. eCollection 2023 Oct.
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Quantitative sonoelastography of the uterine cervix in predicting successful outcome of induction of labour.子宫颈定量弹性成像在预测引产成功结局中的应用
SAGE Open Med. 2023 Apr 13;11:20503121231166637. doi: 10.1177/20503121231166637. eCollection 2023.
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Nomogram Incorporating Multimodal Transvaginal Ultrasound Assessment at 20 to 24 Weeks' Gestation for Predicting Spontaneous Preterm Delivery in Low-Risk Women.纳入孕20至24周多模式经阴道超声评估的列线图,用于预测低风险女性自发性早产。
Int J Womens Health. 2022 Mar 3;14:323-331. doi: 10.2147/IJWH.S356167. eCollection 2022.
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Standardization of measurement of cervical elastography, its reproducibility, and analysis of baseline clinical factors affecting elastographic parameters.宫颈弹性成像测量的标准化、其可重复性以及影响弹性成像参数的基线临床因素分析。
Obstet Gynecol Sci. 2020 Jan;63(1):42-54. doi: 10.5468/ogs.2020.63.1.42. Epub 2019 Dec 27.
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Diagnostic accuracy of cervical elastography in predicting preterm delivery: A systematic review and meta-analysis.宫颈弹性成像预测早产的诊断准确性:一项系统评价和荟萃分析。
Medicine (Baltimore). 2019 Jul;98(29):e16449. doi: 10.1097/MD.0000000000016449.
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Addition of Cervical Elastography May Increase Preterm Delivery Prediction Performance in Pregnant Women with Short Cervix: a Prospective Study.添加宫颈弹性成像可能增加短宫颈孕妇早产预测性能:一项前瞻性研究。
J Korean Med Sci. 2019 Feb 27;34(9):e68. doi: 10.3346/jkms.2019.34.e68. eCollection 2019 Mar 11.
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Prediction of Preterm Birth: Maternal Characteristics, Ultrasound Markers, and Biomarkers: An Updated Overview.早产的预测:母体特征、超声标志物和生物标志物:最新综述
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A soft cervix, categorized by shear-wave elastography, in women with short or with normal cervical length at 18-24 weeks is associated with a higher prevalence of spontaneous preterm delivery.在孕18至24周时,经剪切波弹性成像分类为宫颈柔软的女性,无论宫颈长度短或正常,其自发性早产的患病率都较高。
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Assessment of the Cervix in Pregnant Women Using Shear Wave Elastography: A Feasibility Study.应用剪切波弹性成像技术评估孕妇宫颈:一项可行性研究
Ultrasound Med Biol. 2015 Nov;41(11):2789-97. doi: 10.1016/j.ultrasmedbio.2015.06.020. Epub 2015 Aug 14.
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Usefulness of elastography in predicting the outcome of Foley catheter labour induction.弹性成像在预测 Foley 导管引产结局中的应用价值
Aust N Z J Obstet Gynaecol. 2015 Jun;55(3):245-50. doi: 10.1111/ajo.12331. Epub 2015 Jun 5.
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Strain at the internal cervical os assessed with quasi-static elastography is associated with the risk of spontaneous preterm delivery at ≤34 weeks of gestation.使用准静态弹性成像评估的宫颈内口应变与妊娠≤34周时自然早产的风险相关。
J Perinat Med. 2015 Nov;43(6):657-66. doi: 10.1515/jpm-2014-0382.
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Cervical HI-RTE elastography and pregnancy outcome: a prospective study.宫颈高分辨率弹性成像与妊娠结局:一项前瞻性研究。
Eur J Obstet Gynecol Reprod Biol. 2015 Mar;186:80-4. doi: 10.1016/j.ejogrb.2015.01.016. Epub 2015 Jan 23.
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A universal transvaginal cervical length screening program for preterm birth prevention.一种用于预防早产的通用经阴道宫颈长度筛查计划。
Obstet Gynecol. 2014 Sep;124(3):520-525. doi: 10.1097/AOG.0000000000000428.
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Elastography in predicting preterm delivery in asymptomatic, low-risk women: a prospective observational study.弹性成像预测无症状低风险孕妇早产的前瞻性观察研究。
BMC Pregnancy Childbirth. 2014 Jul 21;14:238. doi: 10.1186/1471-2393-14-238.