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体重指数对急诊腹部手术后并发症及死亡率的影响:肥胖悖论

The effects of body mass index on complications and mortality after emergency abdominal operations: The obesity paradox.

作者信息

Benjamin Elizabeth R, Dilektasli Evren, Haltmeier Tobias, Beale Elizabeth, Inaba Kenji, Demetriades Demetrios

机构信息

Department of Surgery, Division of Acute Care Surgery and Surgical Critical Care, Los Angeles County and University of Southern California Medical Center, Los Angeles, CA, USA.

Department of Surgery, Division of Acute Care Surgery and Surgical Critical Care, Los Angeles County and University of Southern California Medical Center, Los Angeles, CA, USA.

出版信息

Am J Surg. 2017 Nov;214(5):899-903. doi: 10.1016/j.amjsurg.2017.01.023. Epub 2017 Feb 13.

Abstract

BACKGROUND

Recent literature suggests that obesity is protective in critically illness. This study addresses the effect of BMI on outcomes after emergency abdominal surgery (EAS).

METHODS

Retrospective, ACS-NSQIP analysis. All patients that underwent EAS were included. The study population was divided into five groups based on BMI; regression models were used to evaluate the role of obesity in morbidity and mortality.

RESULTS

101,078 patients underwent EAS; morbidity and mortality were 19.5% and 4.5%, respectively. Adjusted mortality was higher in underweight patients (AOR 1.92), but significantly lower in all obesity groups (AOR's 0.73, 0.66, 0.70, 0.70 respectively). Underweight and class III obesity was associated with increased complications (AOR 1.47 and 1.30), while mild obesity was protective (AOR 0.92).

CONCLUSIONS

Underweight patients undergoing EAS have increased morbidity and mortality. Although class III obesity is associated with increased morbidity, overweight and class I obesity were protective. All grades of obesity may be protective against mortality after EAS relative to normal weight patients.

摘要

背景

近期文献表明肥胖在危重病中具有保护作用。本研究探讨了体重指数(BMI)对急诊腹部手术后结局的影响。

方法

回顾性、美国外科医师学会国家外科质量改进计划(ACS-NSQIP)分析。纳入所有接受急诊腹部手术的患者。根据BMI将研究人群分为五组;使用回归模型评估肥胖在发病率和死亡率中的作用。

结果

101,078例患者接受了急诊腹部手术;发病率和死亡率分别为19.5%和4.5%。体重过轻患者的校正死亡率较高(调整后比值比[AOR]为1.92),但在所有肥胖组中显著较低(AOR分别为0.73、0.66、0.70、0.70)。体重过轻和III级肥胖与并发症增加相关(AOR分别为1.47和1.30),而轻度肥胖具有保护作用(AOR为0.92)。

结论

接受急诊腹部手术的体重过轻患者发病率和死亡率增加。虽然III级肥胖与发病率增加相关,但超重和I级肥胖具有保护作用。相对于正常体重患者,所有肥胖等级在急诊腹部手术后可能对死亡率具有保护作用。

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