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肥胖对急诊剖腹手术患者手术结局的影响:一项前瞻性观察研究。

Impact of Obesity on Surgical Outcomes in Patients Undergoing Emergency Laparotomy: A Prospective Observational Study.

作者信息

Marahanumaiah Sudhir, Suresh Nitish, Rajkumar Bhoomika, Priyadarshi Anubhav

机构信息

Department of General Surgery, Kempegowda Institute of Medical Sciences, Bangalore, IND.

出版信息

Cureus. 2025 Jun 12;17(6):e85887. doi: 10.7759/cureus.85887. eCollection 2025 Jun.

Abstract

BACKGROUND AND AIM

Obesity significantly impacts the outcomes of patients undergoing emergency laparotomy. It complicates emergency laparotomy by prolonging operative times, increasing risks due to comorbidities, impairing wound healing, and heightening respiratory complications, leading to higher morbidity, mortality, and healthcare costs. This study aimed to evaluate the impact of obesity on post-operative outcomes in patients undergoing emergency laparotomy at Kempegowda Institute of Medical Sciences (KIMS) Hospital and Research Centre, Bangalore. It focused on the association between body mass index (BMI) and the incidence of post-operative complications, length of hospital stay, and operative time.

MATERIALS AND METHODS

A total of 72 emergency laparotomy patients were grouped by BMI, normal vs. obese, as per the World Health Organization (WHO) classification. Comorbidities and surgical procedures were recorded, excluding laparoscopic cases and underweight patients. Post-operative complications were classified (Clavien-Dindo) and a comprehensive complication index assessed morbidity/mortality during hospitalization.

RESULTS

The study included patients aged 18-88 years, with 48 having normal BMI and 24 classified as obese. Post-operative complications occurred more frequently in obese patients with comorbidities - diabetes (58.3%), hypertension (50%), CKD (4.2%), and IHD (4.2%) - compared to those with normal BMI (diabetes: 14.6%, hypertension: 20%). Notably, 66.7% of normal BMI patients had no complications. Obese patients had significantly longer operative times (by 44.23 minutes) and hospital stays (by 3.5 days).

CONCLUSION

The study demonstrates a significant impact of obesity on post-operative outcomes in patients undergoing emergency laparotomy. Additionally, the data show that a majority of patients with a normal BMI (66.7%), regardless of whether they had comorbid conditions, did not encounter any complications.

摘要

背景与目的

肥胖对接受急诊剖腹手术患者的预后有显著影响。它使急诊剖腹手术复杂化,表现为手术时间延长、合并症导致风险增加、伤口愈合受损以及呼吸并发症增多,进而导致更高的发病率、死亡率和医疗费用。本研究旨在评估肥胖对班加罗尔 Kempegowda 医学科学研究所(KIMS)医院及研究中心接受急诊剖腹手术患者术后结局的影响。研究聚焦于体重指数(BMI)与术后并发症发生率、住院时间及手术时间之间的关联。

材料与方法

根据世界卫生组织(WHO)分类,将 72 例急诊剖腹手术患者按 BMI 分为正常组与肥胖组。记录合并症及手术操作情况,排除腹腔镜手术病例及体重过轻患者。对术后并发症进行分类(Clavien-Dindo 分类),并采用综合并发症指数评估住院期间的发病率/死亡率。

结果

该研究纳入年龄在 18 - 88 岁的患者,其中 48 例 BMI 正常,24 例被归类为肥胖。与 BMI 正常的患者(糖尿病:14.6%,高血压:20%)相比,合并糖尿病(58.3%)、高血压(50%)、慢性肾脏病(4.2%)和缺血性心脏病(4.2%)的肥胖患者术后并发症发生率更高。值得注意的是,66.7%的 BMI 正常患者未出现并发症。肥胖患者的手术时间显著延长(延长 44.23 分钟),住院时间也显著延长(延长 3.5 天)。

结论

该研究表明肥胖对接受急诊剖腹手术患者的术后结局有显著影响。此外,数据显示大多数 BMI 正常的患者(66.7%),无论是否有合并症,均未出现任何并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6234/12163356/35d8f51115db/cureus-0017-00000085887-i01.jpg

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