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病程≥45年的1型糖尿病患者中肩周炎的高患病率:Dialong肩部研究

Very High Prevalence of Frozen Shoulder in Patients With Type 1 Diabetes of ≥45 Years' Duration: The Dialong Shoulder Study.

作者信息

Juel Niels Gunnar, Brox Jens Ivar, Brunborg Cathrine, Holte Kristine Bech, Berg Tore Julsrud

机构信息

Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway; Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway.

Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.

出版信息

Arch Phys Med Rehabil. 2017 Aug;98(8):1551-1559. doi: 10.1016/j.apmr.2017.01.020. Epub 2017 Feb 17.

DOI:10.1016/j.apmr.2017.01.020
PMID:28219686
Abstract

OBJECTIVES

To compare the prevalence of shoulder disorders and self-reported shoulder disability in patients with long-term type 1 diabetes mellitus and diabetes-free subjects; and to explore the association between the long-term glycemic burden and shoulder disability in the diabetes group.

DESIGN

Cross-sectional study of shoulder diagnoses with 30 years' historical data on glycemic burden in patients with diabetes.

SETTING

Diabetics center and a university hospital.

PARTICIPANTS

Subjects attending the Norwegian Diabetics Center in 2015 with type 1 diabetes since 1970 or earlier were eligible (N=136). One hundred and five patients were included, and 102 (50% women; mean age, 61.9y) completed the study together with 73 diabetes-free subjects (55% women; mean age, 62.5y).

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURE

Shoulder diagnoses decided through clinical examination according to scientific diagnostic criteria.

RESULTS

Frozen shoulder was diagnosed in 60 (59%) patients with diabetes and 0 diabetes-free subjects, with a lifetime prevalence of 76% in the diabetes group versus 14% in the diabetes-free subjects. Patients with diabetes had higher disability and higher mean QuickDASH scores (23.0±19.9) than diabetes-free subjects (8.9±12.0), with a mean difference of -14.2 (95% confidence interval, -19.3 to -9.0) points (P<.001). We found an association between chronic hyperglycemia and QuickDASH scores, with a 6.16-point increase in QuickDASH scores per unit increase in glycated hemoglobin A (HbA) (P=.014).

CONCLUSIONS

The point prevalence of frozen shoulder in patients with long-lasting type 1 diabetes was 59%, and the lifetime prevalence was 76%. The diabetes group had more shoulder disability than diabetes-free subjects. The historical HbA level was associated with increased shoulder disability.

摘要

目的

比较长期1型糖尿病患者和非糖尿病患者肩部疾病的患病率及自我报告的肩部功能障碍情况;并探讨糖尿病组长期血糖负担与肩部功能障碍之间的关联。

设计

对糖尿病患者进行肩部诊断的横断面研究,并收集其30年的血糖负担历史数据。

地点

糖尿病中心和一所大学医院。

参与者

2015年就诊于挪威糖尿病中心、自1970年或更早开始患1型糖尿病的患者符合条件(N = 136)。纳入了105例患者,其中102例(50%为女性;平均年龄61.9岁)完成了研究,另有73例非糖尿病受试者(55%为女性;平均年龄62.5岁)参与。

干预措施

不适用。

主要观察指标

根据科学诊断标准通过临床检查确定肩部诊断。

结果

60例(59%)糖尿病患者被诊断为肩周炎,非糖尿病受试者中无肩周炎病例,糖尿病组的终生患病率为76%,非糖尿病组为14%。糖尿病患者的功能障碍程度更高,平均QuickDASH评分(23.0±19.9)高于非糖尿病受试者(8.9±12.0),平均差异为 -14.2分(95%置信区间,-19.3至 -9.0)(P <.001)。我们发现慢性高血糖与QuickDASH评分之间存在关联,糖化血红蛋白A(HbA)每单位增加,QuickDASH评分增加6.16分(P = 0.014)。

结论

长期1型糖尿病患者肩周炎的时点患病率为59%,终生患病率为76%。糖尿病组比非糖尿病受试者有更多的肩部功能障碍。既往HbA水平与肩部功能障碍增加有关。

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