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对因原发性和复发性丹毒住院患者的临床和流行病学评估。

Clinical and epidemiological assessment of patients hospitalized for primary and recurrent erysipelas.

作者信息

Kozłowska Dorota, Myśliwiec Hanna, Kiluk Paulina, Baran Anna, Milewska Anna Justyna, Flisiak Iwona

机构信息

Medical University of Bialystok, Poland; Department of Dermatology and Venereology

Medical University of Bialystok, Poland; Department of Statistics and Medical Informatics

出版信息

Przegl Epidemiol. 2016;70(4):575-584.

Abstract

INTRODUCTION

Erysipelas is a bacterial infection, caused by group A β-hemolytic streptococci (Streptococcus pyogenes), rarely other bacteria. It is characterized by sudden onset and rapid course, with the presence of systemic symptoms.

OBJECTIVE

A retrospective analysis of patients hospitalized for primary and recurrent erysipelas with particular consideration of clinical profile of patients, causes, complications and risk factors of the recurrence.

MATERIAL AND METHODS

We have analyzed the medical records of patients hospitalized for erysipelas at the Dermatology and Venereology Department of the Medical University of Bialystok from 2011 to 2015.

RESULTS

One hundred twenty female (53,8%) and 103 male (46,2%) were included in the study. The median age was 61. The first episode of clinical symptoms was observed in 78% patients, while 22% of them were diagnosed as recurrent erysipelas. Skin lesions in both cases were located in the lower extremities most often. Mechanical trauma was statistically more frequently cause of the disease in men, while venous insufficiency and ulcers in women. Complications such as abscess, ulceration, phlegmon and thrombosis were observed in 22% of patients, significantly more common in men. Patients who were hospitalized more than 10 days were more likely to have higher body mass index and higher indicators of inflammation than patients who required a shorter hospital stay. Recurrent erysipelas was more often diagnosed in patients with co-morbidities, including hypertension, overweight, venous insufficiency and diabetes.

CONCLUSIONS

Erysipelas located in the lower extremities, high temperature on admission, higher indicators of the inflammation, complications and coexistence of obesity and diabetes are the risk factors of the prolonged hospital stay. Primary and recurrent erysipelas have a similar course, severity of the disease and duration of hospitalization.

摘要

引言

丹毒是一种由A组β溶血性链球菌(化脓性链球菌)引起的细菌感染,很少由其他细菌引起。其特点是起病急、病程进展快,并伴有全身症状。

目的

对因原发性和复发性丹毒住院的患者进行回顾性分析,特别考虑患者的临床特征、病因、并发症及复发的危险因素。

材料与方法

我们分析了2011年至2015年在比亚韦斯托克医科大学皮肤科和性病科因丹毒住院患者的病历。

结果

120名女性(53.8%)和103名男性(46.2%)纳入研究。中位年龄为61岁。78%的患者出现首次临床症状,其中22%被诊断为复发性丹毒。两种情况下皮肤病变最常位于下肢。男性中机械性创伤在统计学上更常是该病的病因,而女性中静脉功能不全和溃疡更常见。22%的患者出现脓肿、溃疡、蜂窝织炎和血栓形成等并发症,在男性中明显更常见。住院超过10天的患者比住院时间较短的患者更可能有更高的体重指数和更高的炎症指标。复发性丹毒更常出现在患有合并症的患者中,包括高血压、超重、静脉功能不全和糖尿病。

结论

位于下肢的丹毒、入院时体温高、炎症指标高、并发症以及肥胖和糖尿病并存是住院时间延长的危险因素。原发性和复发性丹毒病程、疾病严重程度及住院时间相似。

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