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循证前列腺癌成像技术在非政府综合医疗保健系统中的应用。

Use of Evidence-Based Prostate Cancer Imaging in a Nongovernmental Integrated Health Care System.

作者信息

Salloum Ramzi G, O'Keeffe-Rosetti Maureen, Ritzwoller Debra P, Hornbrook Mark C, Lafata Jennifer Elston, Nielsen Matthew E

机构信息

University of Florida College of Medicine, Gainesville, FL; Kaiser Permanente Center for Health Research, Portland, OR; Kaiser Permanente Colorado, Denver, CO; and University of North Carolina at Chapel Hill, Chapel Hill, NC.

出版信息

J Oncol Pract. 2017 May;13(5):e441-e450. doi: 10.1200/JOP.2016.018333. Epub 2017 Feb 21.

Abstract

PURPOSE

The overuse of imaging, particularly for staging of low-risk prostate cancer, is well documented and widespread. The existing literature, which focuses on the elderly in fee-for-service settings, points to financial incentives as a driver of overuse and may not identify factors relevant to policy solutions within integrated health care systems, where physicians are salaried.

METHODS

Imaging rates were analyzed among men with incident prostate cancer diagnosed between 2004 and 2011 within the Colorado and Northwest regions of Kaiser Permanente. The sample was stratified according to indication for imaging, ie, high risk for whom imaging was necessary versus low risk for whom imaging was discouraged. Logistic regression was used to model the association between imaging receipt and clinical/demographic patient characteristics by risk strata.

RESULTS

Of the men with low-risk prostate cancer, 35% received nonindicated imaging at diagnosis, whereas 42% of men with high-risk prostate cancer did not receive indicated imaging. Compared with men diagnosed in 2004, those diagnosed in subsequent years were less likely to receive imaging across both risk groups. Men with high-risk cancer diagnosed at ≥ 65 years of age and those with clinical stage ≥ T2 were more likely to receive indicated imaging. Men with comorbidities were more likely to receive imaging across both risk groups. Men with low-risk prostate cancer who had higher median household incomes were less likely to receive nonindicated imaging.

CONCLUSION

Nonindicated imaging for diagnostic staging of patients with low-risk prostate cancer was common, but has decreased over the past decade. These findings suggest that factors other than financial incentives may be driving overuse of imaging.

摘要

目的

影像学检查的过度使用现象,尤其是在低风险前列腺癌分期中的过度使用,有充分记录且广泛存在。现有文献聚焦于按服务收费模式下的老年人,指出经济激励是过度使用的一个驱动因素,且可能未识别出与综合医疗保健系统(医生为 salaried 制)内政策解决方案相关的因素。

方法

对 2004 年至 2011 年期间在凯撒医疗集团科罗拉多和西北地区被诊断为新发前列腺癌的男性患者的影像学检查率进行分析。样本根据影像学检查指征进行分层,即对于高风险患者影像学检查是必要的,而对于低风险患者不鼓励进行影像学检查。采用逻辑回归模型按风险分层对影像学检查接受情况与患者临床/人口统计学特征之间的关联进行建模。

结果

低风险前列腺癌男性患者中,35%在诊断时接受了非必要的影像学检查,而高风险前列腺癌男性患者中有 42%未接受必要的影像学检查。与 2004 年诊断的男性相比,随后几年诊断的男性在两个风险组中接受影像学检查的可能性均较低。年龄≥65 岁且诊断为高风险癌症的男性以及临床分期≥T2 的男性更有可能接受必要的影像学检查。患有合并症的男性在两个风险组中接受影像学检查的可能性均更高。家庭收入中位数较高的低风险前列腺癌男性接受非必要影像学检查的可能性较小。

结论

低风险前列腺癌患者诊断分期时的非必要影像学检查很常见,但在过去十年中有所减少。这些发现表明,除经济激励外,其他因素可能也在推动影像学检查的过度使用。

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