袖状胃切除术与胃旁路手术的安全性和有效性：德黑兰肥胖治疗研究（TOTS）的一年结果
Safety and effectiveness of sleeve gastrectomy versus gastric bypass: one-year results of Tehran Obesity Treatment Study (TOTS).
作者信息
Barzin Maryam, Khalaj Alireza, Motamedi Mohammad Ali, Shapoori Pravin, Azizi Fereidoun, Hosseinpanah Farhad
机构信息
Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Faculty of Medicine, Shahed University, Tehran, Iran.
出版信息
Gastroenterol Hepatol Bed Bench. 2016 Dec;9(Suppl1):S62-S69.
AIM
We aimed to compare the effectiveness and safety of sleeve gastrectomy versus gastric bypass at one-year.
BACKGROUND
Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the two most commonly performed bariatric procedures worldwide.
METHODS
Patients from a prospectively collected database who presented to a specialized bariatric center and underwent a primary bariatric procedure between March 2013 and April 2015 were included and compared regarding major and minor complication rates and weight loss parameters at 6 and 12 months.
RESULTS
A total of 513 patients with a mean age of 37.5±12.5, 82.6 % female and mean body mass index (BMI) of 44.1±6.3 kg/m2 were included in our analysis: 73.3% underwent SG and 26.7% underwent RYGB. Major and minor complication rates were 7.1 and 2.6% for SG vs. 9.5 and 2.2% for the RYGB, respectively (=NS). The operative and anesthesia time in SG patients were significantly shorter than in RYGB patients (P<0.001). SG and RYBG patients achieved similar excess weight loss at one year (75.4±20.5% vs. 71.8±26.3%, respectively, =NS). Baseline BMI was the only predictive factor for weight loss at one year (OR: 0.901, CI: 0.827-0.982, <0.017).
CONCLUSION
RYGB and SG both showed similar one-year safety and effectiveness. Long-term studies are needed to complement these findings.
目的
我们旨在比较袖状胃切除术与胃旁路术在一年时的有效性和安全性。
背景
Roux-en-Y胃旁路术（RYGB）和袖状胃切除术（SG）是全球最常开展的两种减肥手术。
方法
纳入前瞻性收集数据库中2013年3月至2015年4月期间就诊于一家专业减肥中心并接受初次减肥手术的患者，比较6个月和12个月时的主要和次要并发症发生率及体重减轻参数。
结果
我们的分析共纳入513例患者，平均年龄37.5±12.5岁，女性占82.6%，平均体重指数（BMI）为44.1±6.3kg/m²：73.3%接受了SG，26.7%接受了RYGB。SG的主要和次要并发症发生率分别为7.1%和2.6%，而RYGB分别为9.5%和2.2%（=无统计学差异）。SG患者的手术和麻醉时间显著短于RYGB患者（P<0.001）。SG和RYBG患者在一年时实现了相似的超重减轻（分别为75.4±20.5%和71.8±26.3%，=无统计学差异）。基线BMI是一年时体重减轻的唯一预测因素（比值比：0.901，可信区间：0.827 - 0.982，<0.017）。
结论
RYGB和SG均显示出相似的一年安全性和有效性。需要长期研究来补充这些发现。
Zotero 插件