皮肤症状作为自身炎症性疾病的诊断线索。
Skin symptoms as diagnostic clue for autoinflammatory diseases.
作者信息
Moreira Alvaro, Torres Barbara, Peruzzo Juliano, Mota Alberto, Eyerich Kilian, Ring Johannes
机构信息
Department of Dermatology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland.
出版信息
An Bras Dermatol. 2017 Jan-Feb;92(1):72-80. doi: 10.1590/abd1806-4841.20175208.
Autoinflammatory disorders are immune-mediated diseases with increased production of inflammatory cytokines and absence of detectable autoantibodies. They course with recurrent episodes of systemic inflammation and fever is the most common symptom. Cutaneous manifestations are prevalent and important to diagnosis and early treatment of the syndromes. The purpose of this review is to emphasize to dermatologists the skin symptoms present in these syndromes in order to provide their early diagnosis.
自身炎症性疾病是免疫介导的疾病，其炎症细胞因子产生增加且不存在可检测到的自身抗体。它们伴有全身性炎症的反复发作，发热是最常见的症状。皮肤表现很常见，对这些综合征的诊断和早期治疗很重要。本综述的目的是向皮肤科医生强调这些综合征中出现的皮肤症状，以便早期诊断。
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