生化指标无异常的输血后非甲非乙型肝炎会干扰甲型肝炎病毒的重叠感染。

Biochemically silent posttransfusion non-A, non-B hepatitis interferes with superinfection by hepatitis A virus.

作者信息

Bradley D W, Krawczynski K, Humphrey C D, McCaustland K A

机构信息

Hepatitis Branch, Center for Infectious Diseases, Atlanta, Ga. 30333.

出版信息

Intervirology. 1987;27(2):86-90. doi: 10.1159/000149724.

DOI:10.1159/000149724

PMID:2822600

Abstract

Superinfection of a silently non-A, non-B (NANB)-infected chimpanzee with hepatitis A virus (HAV) resulted in minimal liver enzyme elevations, lack of detectable HAV in stool, and questionable presence of HAV antigen in liver biopsy specimens obtained during the expected period of virus replication. Our findings indicate that even biochemically silent NANB hepatitis can strongly interfere with infection by at least one other hepatotrophic virus.

摘要

一只无症状非甲非乙型（NANB）感染的黑猩猩感染甲型肝炎病毒（HAV）后，肝酶仅有轻微升高，粪便中未检测到可检出的HAV，在预期病毒复制期获取的肝活检标本中HAV抗原的存在情况存疑。我们的研究结果表明，即使是生化指标无症状的NANB肝炎也会强烈干扰至少另一种嗜肝病毒的感染。