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In-vitro activity of LY146032 against Staphylococcus aureus, Listeria monocytogenes, Corynebacterium JK, and Bacillus spp., in comparison with various antibiotics.

作者信息

Van der Auwera P, Grenier P, Klastersky J

机构信息

Service de Médecine, Université Libre de Bruxelles, Belgium.

出版信息

J Antimicrob Chemother. 1987 Aug;20(2):209-12. doi: 10.1093/jac/20.2.209.

DOI:10.1093/jac/20.2.209
PMID:2822648
Abstract

The in-vitro activity of LY146032 was studied against Staphylococcus aureus, Listeria monocytogenes, Corynebacterium JK, and Bacillus spp. in comparison with several agents with action against Gram-positive bacteria. LY146032 showed an MIC90 of 0.4 mg/l for S. aureus, regardless of the resistance to penicillin or oxacillin. LY146032 was equivalent in activity to ciprofloxacin and vancomycin against S. aureus and moderately active against other species tested (MIC90, 0.8-3.2 mg/l).

摘要

相似文献

1
In-vitro activity of LY146032 against Staphylococcus aureus, Listeria monocytogenes, Corynebacterium JK, and Bacillus spp., in comparison with various antibiotics.
J Antimicrob Chemother. 1987 Aug;20(2):209-12. doi: 10.1093/jac/20.2.209.
2
Comparative in vitro activity of LY146032 (daptomycin), a new lipopeptide antimicrobial.新型脂肽类抗菌药物LY146032（达托霉素）的体外活性比较
Eur J Clin Microbiol. 1987 Feb;6(1):100-3. doi: 10.1007/BF02097211.
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Eur J Clin Microbiol. 1987 Feb;6(1):91-6. doi: 10.1007/BF02097209.
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Comparative in-vitro activity of LY146032 and eight other antibiotics against gram-positive bacteria isolated from children.LY146032与其他八种抗生素对从儿童中分离出的革兰氏阳性菌的体外活性比较
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Comparative in-vitro activity of LY146032 a new peptolide, with vancomycin and eight other agents against gram-positive organisms.新型缩肽类抗生素LY146032与万古霉素及其他八种药物对革兰氏阳性菌的体外活性比较
J Antimicrob Chemother. 1987 Aug;20(2):191-6. doi: 10.1093/jac/20.2.191.
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J Antimicrob Chemother. 1987 Oct;20(4):505-11. doi: 10.1093/jac/20.4.505.
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In-vitro susceptibility of gram-positive cocci to LY146032 teicoplanin, sodium fusidate, vancomycin, and rifampicin.革兰氏阳性球菌对LY146032、替考拉宁、夫西地酸钠、万古霉素和利福平的体外敏感性。
J Antimicrob Chemother. 1987 Aug;20(2):197-202. doi: 10.1093/jac/20.2.197.
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Bactericidal activity and killing rate of serum in volunteers receiving vancomycin or teicoplanin with and without amikacin given intravenously.接受静脉注射万古霉素或替考拉宁（分别联合或不联合阿米卡星）的志愿者血清的杀菌活性和杀菌率。
J Antimicrob Chemother. 1987 May;19(5):623-35. doi: 10.1093/jac/19.5.623.

引用本文的文献

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Management of listeriosis.李斯特菌病的管理
Clin Microbiol Rev. 1997 Apr;10(2):345-57. doi: 10.1128/CMR.10.2.345.
2
Ex vivo study of serum bactericidal titers and killing rates of daptomycin (LY146032) combined or not combined with amikacin compared with those of vancomycin.与万古霉素相比，达托霉素（LY146032）联合或不联合阿米卡星的血清杀菌效价和杀菌率的体外研究。
Antimicrob Agents Chemother. 1989 Oct;33(10):1783-90. doi: 10.1128/AAC.33.10.1783.