In-vitro activity of LY146032 against Staphylococcus aureus, Listeria monocytogenes, Corynebacterium JK, and Bacillus spp., in comparison with various antibiotics.
作者信息
Van der Auwera P, Grenier P, Klastersky J
机构信息
Service de Médecine, Université Libre de Bruxelles, Belgium.
出版信息
J Antimicrob Chemother. 1987 Aug;20(2):209-12. doi: 10.1093/jac/20.2.209.
PMID:2822648
Abstract
The in-vitro activity of LY146032 was studied against Staphylococcus aureus, Listeria monocytogenes, Corynebacterium JK, and Bacillus spp. in comparison with several agents with action against Gram-positive bacteria. LY146032 showed an MIC90 of 0.4 mg/l for S. aureus, regardless of the resistance to penicillin or oxacillin. LY146032 was equivalent in activity to ciprofloxacin and vancomycin against S. aureus and moderately active against other species tested (MIC90, 0.8-3.2 mg/l).
摘要
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