Department of Public Health, Kitasato University School of Medicine, Sagamihara, Japan.
Takemi Program in International Health, Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, USA.
Sci Rep. 2017 Feb 23;7:43204. doi: 10.1038/srep43204.
We examined occupational and industrial differences in lung, gastric, and colorectal cancer risk among Japanese men of working age (25-64 years) using the 2010 Japanese national survey data for occupation and industry-specific death rates. Poisson regression models were used to estimate the age-adjusted incident rate ratios by lung, gastric, and colorectal cancers, with manufacturing used as the referent occupation or industry. Unemployed Japanese men and those in manufacturing had an 8-11-fold increased risk of lung, gastric and colorectal cancer. The highest mortality rates for lung and colorectal cancer by occupation were "administrative and managerial" (by occupation) and "mining" (by industry). For gastric cancer, the highest mortality rate was "agriculture" (by occupation) and "mining" (by industry). By occupation; Japanese men in service occupations, those in administrative and managerial positions, those in agriculture, forestry and fisheries, and those in professional and engineering categories had higher relative mortality risks for lung, gastric, and colorectal cancers. By industry; mining, electricity and gas, fisheries, and agriculture and forestry had the higher mortality risks for those cancers. Unemployed men had higher mortality rates than men in any occupation and industry for all three cancers. Overall, this study suggests that for Japanese men, occupations and industries may be a key social determinant of health.
我们使用 2010 年日本全国职业和行业特定死亡率调查数据，研究了日本处于工作年龄（25-64 岁）的男性的职业和行业差异与肺癌、胃癌和结直肠癌风险之间的关系。我们采用泊松回归模型，以制造业为参照职业或行业，估计了年龄调整后的肺癌、胃癌和结直肠癌的发病率比值。失业的日本男性和制造业男性患肺癌、胃癌和结直肠癌的风险增加了 8-11 倍。职业方面，肺癌和结直肠癌死亡率最高的是“管理和行政”（职业）和“采矿业”（行业）。对于胃癌，死亡率最高的是“农业”（职业）和“采矿业”（行业）。就职业而言，服务行业、管理和行政岗位、农业、林业和渔业以及专业和工程类别的日本男性患肺癌、胃癌和结直肠癌的相对死亡风险更高。就行业而言，采矿业、电力和燃气、渔业以及农业和林业的死亡率更高。对于所有三种癌症，失业男性的死亡率均高于任何职业和行业的男性。总的来说，这项研究表明，对于日本男性而言，职业和行业可能是健康的一个关键社会决定因素。
