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职业特征与退休后无残疾生存:来自 ASPREE 研究的探索性分析。

Occupational characteristics and disability-free survival after retirement age: an exploratory analysis from the ASPREE study.

机构信息

School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.

School of Health Sciences, The University of Melbourne, Melbourne, VIC, Australia.

出版信息

Front Public Health. 2023 Dec 15;11:1191343. doi: 10.3389/fpubh.2023.1191343. eCollection 2023.

Abstract

BACKGROUND

Certain occupational characteristics have been linked with poor health and reduced longevity. However, the association between occupational characteristics and survival free of disability in a post-retirement age group has not been investigated.

METHODS

We investigated outcomes in 12,215 healthy older Australian adults in the Aspirin in Reducing Events in the Elderly (ASPREE) and ASPREE Longitudinal Study of Older Persons (ALSOP) sub-study. The ISCO-88 major occupational groups, settings, and activity levels were assigned based on free-text job descriptions. The Finnish Job Exposure Matrix was used to assign occupational characteristics to the three longest-held jobs. The primary endpoint, disability-free survival, was defined as a composite measure of death, dementia, or persistent physical disability. The endpoint of all-cause mortality was analyzed separately. Because of multiple exploratory analyses, only those associations with a two-sided value of p less than 0.005 were considered statistically significant. Cox proportional hazard models were used to calculate adjusted hazard ratios.

RESULTS

Having worked in an 'elementary' occupation was associated with a reduction in disability-free survival. A specific impact on disability-free survival was observed among those whose work had involved high accident risk and adverse social climate. No significant relationship was identified with those previously exposed to sedentary work, vigorous physical activity, work primarily outdoors, or a range of other occupational characteristics. All-cause mortality was not increased among any of the occupational groups.

CONCLUSION

This exploratory study found a reduction in disability-free survival among people who worked in 'elementary' occupations, with specific risks associated with occupations involving high accident risks and adverse social climate.

摘要

背景

某些职业特征与健康状况不佳和寿命缩短有关。然而,职业特征与退休后年龄组生存无残疾之间的关联尚未被研究。

方法

我们研究了 12215 名健康的澳大利亚老年人在阿司匹林减少老年人事件(ASPREE)和 ASPREE 老年人纵向研究(ALSOP)子研究中的结局。根据自由文本的工作描述,将 ISCO-88 主要职业群体、工作环境和活动水平进行了分配。芬兰职业暴露矩阵被用于将职业特征分配给三个最长时间的工作。主要终点,无残疾生存,被定义为死亡、痴呆或持续性身体残疾的综合衡量标准。全因死亡率终点分别进行了分析。由于进行了多次探索性分析,只有双侧 p 值小于 0.005 的那些关联被认为具有统计学意义。使用 Cox 比例风险模型计算调整后的危险比。

结果

从事“基础”职业与无残疾生存的降低有关。在工作中存在高事故风险和不良社会氛围的人群中,观察到对无残疾生存的特定影响。与先前暴露于久坐工作、剧烈体力活动、主要在户外工作或其他一系列职业特征的人群之间没有显著关系。在任何职业群体中,全因死亡率均未增加。

结论

这项探索性研究发现,从事“基础”职业的人群无残疾生存降低,与高事故风险和不良社会氛围相关的职业存在特定风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1d8/10773837/178f126bd7ff/fpubh-11-1191343-g001.jpg

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