de Groot Patricia, Munden Reginald F
Division of Diagnostic Imaging, Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1478, Houston, TX 77030, USA.
Radiol Clin North Am. 2012 Sep;50(5):863-76. doi: 10.1016/j.rcl.2012.06.006.
The greatest risk by far for developing lung cancer is cigarette smoking, but age, radon exposure, environmental pollution, occupational exposures, gender, race, and pre-existing lung disease also are important contributors. However, not all people with these risk factors develop lung cancer, and some without any known risk factor do, indicating the importance of genetic influences. Future advances in understanding and treating lung cancer will be based on genetic analysis. The most effective preventive measure is to never start or to stop cigarette smoking.
目前，患肺癌的最大风险因素是吸烟，但年龄、氡暴露、环境污染、职业暴露、性别、种族以及既往肺部疾病也都是重要的促成因素。然而，并非所有有这些风险因素的人都会患肺癌，而一些没有任何已知风险因素的人却会患肺癌，这表明了基因影响的重要性。未来在肺癌理解和治疗方面的进展将基于基因分析。最有效的预防措施是从不开始吸烟或戒烟。
