Kim D, Franco G A, Shigehara H, Asaumi J, Hildenbrand P
From the Department of Radiology (D.K., P.H.), Lahey Hospital and Medical Center, Burlington, Massachusetts.
Commonwealth Radiology Associates (G.A.F.), Brockton, Massachusetts.
AJNR Am J Neuroradiol. 2017 Apr;38(4):789-794. doi: 10.3174/ajnr.A5096. Epub 2017 Feb 23.
Osteoma cutis of the face represents a primary or secondary formation of ossific foci in the facial skin. Its primary form has been sparsely described in the plastic surgery and dermatology literature. As radiologists, we routinely encounter incidental, very small facial calcified nodules on CT studies performed for a variety of unrelated reasons. We hypothesized that this routinely encountered facial calcification represents primary miliary osteoma cutis and is a common, benign, age-related finding.
We retrospectively reviewed 1315 consecutive sinus CTs obtained during an 8-month period and their associated demographics. The number of dermal radiopaque lesions with Hounsfield units of >150 was counted, and we analyzed the association between the prevalence of these lesions and patients' demographics with logistic regression methods.
Five hundred ninety-nine males and 716 females from 4 to 90 years of age were included in the study (mean, 52 versus 51 years; = .259). Among these, 252 males and 301 females had small facial calcified nodules (42.1% versus 42.0%, = .971). The patient's age was a statistically significant predictor for having facial calcified nodules (odds ratio = 1.02, < .001), while the patient's sex was not ( = .826).
Facial calcified nodules, observed in routine head and face CT imaging, are common, benign, age-related findings, which have been largely overlooked in the radiology literature. It is a manifestation of primary miliary osteoma cutis.
面部皮肤骨瘤是指面部皮肤中骨化灶的原发性或继发性形成。其原发性形式在整形外科学和皮肤病学文献中鲜有描述。作为放射科医生,我们在因各种无关原因进行的CT检查中经常会偶然发现非常小的面部钙化结节。我们推测这种在常规检查中遇到的面部钙化代表原发性粟粒性皮肤骨瘤,是一种常见的、良性的、与年龄相关的表现。
我们回顾性分析了在8个月期间连续获得的1315例鼻窦CT及其相关的人口统计学数据。统计了Hounsfield单位>150的皮肤不透射线病变的数量,并采用逻辑回归方法分析了这些病变的患病率与患者人口统计学特征之间的关联。
本研究纳入了4至90岁的599名男性和716名女性(平均年龄分别为52岁和51岁;P = 0.259)。其中,252名男性和301名女性有小的面部钙化结节(42.1%对42.0%,P = 0.971)。患者的年龄是面部钙化结节的统计学显著预测因素(优势比 = 1.02,P < 0.001),而患者的性别不是(P = 0.826)。
在常规头面部CT成像中观察到的面部钙化结节是常见的、良性的、与年龄相关的表现,在放射学文献中很大程度上被忽视了。它是原发性粟粒性皮肤骨瘤的一种表现。