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Characteristics of type 1 and 2 CNV in exudative AMD in OCT-Angiography.

作者信息

Farecki Marie-Louise, Gutfleisch Matthias, Faatz Henrik, Rothaus Kai, Heimes Britta, Spital Georg, Lommatzsch Albrecht, Pauleikhoff Daniel

机构信息

Department of Opthalmology, St. Franziskus Hospital, Hohenzollernring 74, 48145, Münster, Germany.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2017 May;255(5):913-921. doi: 10.1007/s00417-017-3588-y. Epub 2017 Feb 23.


DOI:10.1007/s00417-017-3588-y
PMID:28233061
Abstract

BACKGROUND: With FA and SD-OCT, different types of CNV in exudative AMD may be differentiated: type 1 CNV (within the sub-RPE space, typically corresponding to angiographically occult CNV), type 2 CNV (within the subretinal space, typically corresponding to angiographically classic CNV) and type 3 NV (intraretinal retinal angiomatous proliferation). OCT-angiography (OCT-A) is a new method to visualize vasculature based on flow characteristics. A correlation of type 1 and 2 CNV was performed. METHODS: Thirty-six eyes (17 type 1 CNV, 9 combined type 1 and 2 CNV, and 10 type 2 CNV) of 36 patients were examined by FA, SD-OCT and OCT-A. Standardized OCT-A segmentations were performed at the level of mid-choroid, choriocapillaris (CC), RPE and outer retina. On these images the size and demarcation of CNV lesions were classified: "not distinguishable", "minor" or "sharp" demarcation. Furthermore, the size of the different CNV subtypes was determined and compared. RESULTS: Both types of CNV were visible in OCT-A. They could be detected on the slabs "mid-choroid", "CC" and "RPE". While type 1 CNV showed most often a minor demarcation from the surrounding vasculature, type 2 CNV showed nearly always a sharp demarcation. In addition, type 2 CNV extended into the slab "outer retina" and were much smaller than type 1 CNV. CONCLUSIONS: Different types of CNV in exudative AMD can be visualized and differentiated with OCT-A. Type 1 CNV were larger with minor demarcation from the surrounding vasculature and were visible on the slab "mid-choroid", "CC" and "RPE". In contrast, type 2 CNV demonstrated a sharp demarcation from the surrounding vasculature reaching the slab "outer retina".

摘要

相似文献

[1]
Characteristics of type 1 and 2 CNV in exudative AMD in OCT-Angiography.

Graefes Arch Clin Exp Ophthalmol. 2017-5

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[7]
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[8]
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[9]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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本文引用的文献

[1]
Optical Coherence Tomography Angiography Using the Optovue Device.

Dev Ophthalmol. 2016

[2]
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF TIME COURSE OF CHOROIDAL NEOVASCULARIZATION IN RESPONSE TO ANTI-ANGIOGENIC TREATMENT.

Retina. 2015-11

[3]
ASSOCIATION BETWEEN CHANGES IN MACULAR VASCULATURE IN OPTICAL COHERENCE TOMOGRAPHY- AND FLUORESCEIN- ANGIOGRAPHY AND DISTRIBUTION OF MACULAR PIGMENT IN TYPE 2 IDIOPATHIC MACULAR TELANGIECTASIA.

Retina. 2015-11

[4]
LONGITUDINAL OPTICAL COHERENCE TOMOGRAPHY-ANGIOGRAPHY STUDY OF TYPE 2 NAIVE CHOROIDAL NEOVASCULARIZATION EARLY RESPONSE AFTER TREATMENT.

Retina. 2015-11

[5]
CHARACTERIZING THE EFFECT OF ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ON TREATMENT-NAIVE CHOROIDAL NEOVASCULARIZATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Retina. 2015-11

[6]
TYPE 2 NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Retina. 2015-11

[7]
OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY VERSUS TRADITIONAL MULTIMODAL IMAGING IN ASSESSING THE ACTIVITY OF EXUDATIVE AGE-RELATED MACULAR DEGENERATION: A New Diagnostic Challenge.

Retina. 2015-11

[8]
[OCT Angiography - Is this the Future for Macular Diagnosis?].

Klin Monbl Augenheilkd. 2015-9

[9]
Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration.

Am J Ophthalmol. 2015-10

[10]
OCT angiography and sequential quantitative analysis of type 2 neovascularization after ranibizumab therapy.

Eye (Lond). 2015-7

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