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3
Finite-element modeling of intrastromal ring segment implantation into a hyperelastic cornea.基质内环段植入超弹性角膜的有限元建模。
Invest Ophthalmol Vis Sci. 2013 Jan 30;54(1):881-9. doi: 10.1167/iovs.12-10852.
4
New clinical pathways for keratoconus.圆锥角膜的新临床路径。
Eye (Lond). 2013 Mar;27(3):329-39. doi: 10.1038/eye.2012.257. Epub 2012 Dec 21.
5
Outcome analysis of intracorneal ring segments for the treatment of keratoconus based on visual, refractive, and aberrometric impairment.基于视觉、屈光和像差损伤的角膜环段治疗圆锥角膜的疗效分析。
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Cornea. 2012 Jul;31(7):740-5. doi: 10.1097/ICO.0b013e318219aa7a.
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Sequential versus concurrent KERARINGS insertion and corneal collagen cross-linking for keratoconus.序贯与同期 KERARINGS 植入联合角膜胶原交联术治疗圆锥角膜。
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Intracorneal ring segments in ectatic corneal disease - a review.膨胀性角膜疾病中的角膜内环段 - 综述。
Clin Exp Ophthalmol. 2010 Mar;38(2):154-67. doi: 10.1111/j.1442-9071.2010.02197.x.
9
Complications of intrastromal corneal ring segment implantation using a femtosecond laser for channel creation: a survey of 850 eyes with keratoconus.基质内角膜环段植入术使用飞秒激光创建通道的并发症:圆锥角膜 850 眼调查。
Acta Ophthalmol. 2011 Feb;89(1):54-7. doi: 10.1111/j.1755-3768.2009.01605.x.
10
Refractive and topographic results of transepithelial cross-linking treatment in eyes with intacs.使用Intacs的眼睛经上皮交联治疗的屈光和地形图结果。
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使用蔡司Visumax飞秒激光进行角膜环植入术治疗圆锥角膜患者。

Keraring implantation using the Zeiss Visumax femtosecond laser in the management of patients with keratoconus.

作者信息

Wilde C L, Naylor S G, Varga Z, Morrell A, Ball J L

机构信息

Department of Ophthalmology, St James's University Hospital, Leeds, UK.

出版信息

Eye (Lond). 2017 Jun;31(6):916-923. doi: 10.1038/eye.2017.13. Epub 2017 Feb 24.

DOI:10.1038/eye.2017.13
PMID:28234352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5518832/
Abstract

PurposeTo evaluate the safety and efficacy of implanted Kerarings in patients with mild, moderate, and severe keratoconus.Patients and methodsA 12-month retrospective case series of 70 eyes of 70 patients who underwent Keraring implantation with the Zeiss Visumax femtosecond laser. Patients were stratified into three groups according to their topography as mild (mean K <48 D) moderate (48-55 D) or severe (>55 D). Main outcome measures were visual acuity, manifest refraction, and corneal topography. Complications were recorded.ResultsA total of 66 patients completed the 12-month follow-up. In all, 4 rings were explanted, 3 due to no improvement in visual function and 1 due to corneal neovascularization. Also, 4 rings were repositioned. In mild disease (n=28), BCVA increased to 0.10 logMAR, sphere decreased to -1.54 D, cylinder decreased to 2.54 D, Kmax decreased to 46.25 D, and keratometric astigmatism to 3.88 D (P<0.01 for each compared with preoperative values). No patients lost vision. In moderate disease (n=27), sphere decreased to -4.06 D, cylinder decreased to 3.47 D, Kmax decreased to 51.69 D, and keratometric astigmatism to 4.56 D (P<0.05 for each compared with preoperative values). In severe disease (n=11), BCVA increased to 0.34 logMAR, Kmax decreased to 57.65 D, and keratometric astigmatism to 5.07 D (P<0.05 for each compared with preoperative values).ConclusionFemtosecond laser-assisted Keraring implantation is a safe and minimally invasive treatment option to improve the refraction and visual function in patients with keratoconus. Patients with mild keratoconus are more likely to have a favourable outcome following Keraring implantation.

摘要

目的

评估植入Kerarings对轻、中、重度圆锥角膜患者的安全性和有效性。

患者与方法

一项为期12个月的回顾性病例系列研究,纳入70例患者的70只眼,这些患者均接受了蔡司Visumax飞秒激光辅助的Kerarings植入术。根据角膜地形图将患者分为三组:轻度(平均角膜曲率<48 D)、中度(48 - 55 D)或重度(>55 D)。主要观察指标为视力、显验光和角膜地形图。记录并发症情况。

结果

共有66例患者完成了12个月的随访。总共取出了4个环,3个是因为视功能无改善,1个是因为角膜新生血管形成。另外,4个环进行了重新定位。在轻度圆锥角膜组(n = 28),最佳矫正视力(BCVA)提高到0.10 logMAR,球镜度数降至 - 1.54 D,柱镜度数降至2.54 D,最大角膜曲率(Kmax)降至46.25 D,角膜散光降至3.88 D(与术前值相比,每项P < 0.01)。没有患者视力丧失。在中度圆锥角膜组(n = 27),球镜度数降至 - 4.06 D,柱镜度数降至3.47 D,Kmax降至51.69 D,角膜散光降至4.56 D(与术前值相比,每项P < 0.05)。在重度圆锥角膜组(n = 11),BCVA提高到0.34 logMAR,Kmax降至57.65 D,角膜散光降至5.07 D(与术前值相比,每项P < 0.05)。

结论

飞秒激光辅助的Kerarings植入术是一种安全且微创的治疗方法,可改善圆锥角膜患者的屈光和视功能。轻度圆锥角膜患者在植入Kerarings后更有可能获得良好的治疗效果。