Moorfields Eye Hospital, London, UK.
Eye (Lond). 2013 Mar;27(3):329-39. doi: 10.1038/eye.2012.257. Epub 2012 Dec 21.
Pre-2000, the clinical management of keratoconus centred on rigid contact lens fitting when spectacle corrected acuity was no longer adequate, and transplantation where contact lens wear failed. Over the last decade, outcome data have accumulated for new interventions including corneal collagen crosslinking, intracorneal ring implantation, topographic phototherapeutic keratectomy, and phakic intraocular lens implantation. We review the current evidence base for these interventions and their place in new management pathways for keratoconus under two key headings: corneal shape stabilisation and visual rehabilitation.
2000 年以前，当常规眼镜矫正视力不再足够时，临床上角膜塑形术的管理集中在硬性角膜接触镜的适配上，而当接触镜佩戴失败时则进行移植。在过去的十年中，已经积累了包括角膜胶原交联、角膜内环植入、角膜地形光疗性切削术和有晶状体眼人工晶状体植入在内的新干预措施的结果数据。我们根据角膜形状稳定和视觉康复这两个关键标题，回顾了这些干预措施的现有证据基础及其在圆锥角膜新管理途径中的地位。
