Suppr超能文献

基于视觉、屈光和像差损伤的角膜环段治疗圆锥角膜的疗效分析。

Outcome analysis of intracorneal ring segments for the treatment of keratoconus based on visual, refractive, and aberrometric impairment.

机构信息

Keratoconus Unit, Vissum Corporation, Alicante, Spain.

出版信息

Am J Ophthalmol. 2013 Mar;155(3):575-584.e1. doi: 10.1016/j.ajo.2012.08.020. Epub 2012 Dec 4.

Abstract

PURPOSE

To analyze the outcomes of intracorneal ring segment (ICRS) implantation for the treatment of keratoconus based on preoperative visual impairment.

DESIGN

Multicenter, retrospective, nonrandomized study.

METHODS

A total of 611 eyes of 361 keratoconic patients were evaluated. Subjects were classified according to their preoperative corrected distance visual acuity (CDVA) into 5 different groups: grade I, CDVA of 0.90 or better; grade II, CDVA equal to or better than 0.60 and worse than 0.90; grade III, CDVA equal to or better than 0.40 and worse than 0.60; grade IV, CDVA equal to or better than 0.20 and worse than 0.40; and grade plus, CDVA worse than 0.20. Success and failure indices were defined based on visual, refractive, corneal topographic, and aberrometric data and evaluated in each group 6 months after ICRS implantation.

RESULTS

Significant improvement after the procedure was observed regarding uncorrected distance visual acuity in all grades (P < .05). CDVA significantly decreased in grade I (P < .01) but significantly increased in all other grades (P < .05). A total of 37.9% of patients with preoperative CDVA 0.6 or better gained 1 or more lines of CDVA, whereas 82.8% of patients with preoperative CDVA 0.4 or worse gained 1 or more lines of CDVA (P < .01). Spherical equivalent and keratometry readings showed a significant reduction in all grades (P ≤ .02). Corneal higher-order aberrations did not change after the procedure (P ≥ .05).

CONCLUSIONS

Based on preoperative visual impairment, ICRS implantation provides significantly better results in patients with a severe form of the disease. A notable loss of CDVA lines can be expected in patients with a milder form of keratoconus.

摘要

目的

根据术前视力损害情况,分析角膜内环段(ICRS)植入治疗圆锥角膜的效果。

设计

多中心、回顾性、非随机研究。

方法

共评估了 361 例圆锥角膜患者的 611 只眼。根据术前矫正远视力(CDVA)将受试者分为 5 个不同组别:I 级,CDVA 为 0.90 或更好;II 级,CDVA 等于或好于 0.60 但差于 0.90;III 级,CDVA 等于或好于 0.40 但差于 0.60;IV 级,CDVA 等于或好于 0.20 但差于 0.40;加级,CDVA 差于 0.20。根据视力、屈光、角膜地形图和像差数据,在 ICRS 植入术后 6 个月定义成功和失败指数,并在每个组中进行评估。

结果

所有级别术后未矫正远视力均有显著改善(P<.05)。I 级 CDVA 显著下降(P<.01),但所有其他级别均显著增加(P<.05)。术前 CDVA 为 0.6 或更好的患者中有 37.9%的患者获得了 1 行或更多行的 CDVA,而术前 CDVA 为 0.4 或更差的患者中有 82.8%的患者获得了 1 行或更多行的 CDVA(P<.01)。所有级别球镜和角膜曲率读数均显著降低(P≤.02)。术后角膜高阶像差无变化(P≥.05)。

结论

根据术前视力损害情况,ICRS 植入在疾病严重程度较高的患者中提供了显著更好的结果。在疾病较轻的患者中,CDVA 线的显著损失是可以预期的。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验