Lung Tom, Howard Kirsten, Etherton-Beer Christopher, Sim Moira, Lewin Gill, Arendts Glenn
The George Institute for Global Health, University of Sydney, Sydney, New South Wales, Australia.
Sydney Medical School, School of Public Health, University of Sydney, Sydney, New South Wales, Australia.
PLoS One. 2017 Feb 24;12(2):e0172796. doi: 10.1371/journal.pone.0172796. eCollection 2017.
Accurately assessing changes in the quality of life of older people living permanently in nursing homes is important. The multi-attribute utility instrument most commonly used and recommended to assess health-related quality of life in the nursing home population is the three-level EuroQol EQ-5D-3L. To date, there have been no studies using the Health Utilities Index Mark III (HUI3). The purpose of this study was to compare the level of agreement and sensitivity to change of the EQ-5D-3L and HUI3 in a nursing home population.
EQ-5D-3L and HUI3 scores were measured as part of a cluster randomised controlled trial of nurse led care coordination in a nursing home population in Perth, Western Australia at baseline and 6-month follow up.
Both measures were completed for 199 residents at baseline and 177 at 6-month follow-up. Mean baseline utility scores for EQ-5D-3L (0.45; 95% CI 0.41-0.49) and HUI3 (0.15; 95% CI 0.10-0.20) were significantly different (Wilcoxon signed rank test, p<0.01) and agreement was poor to moderate between absolute scores from each instrument (intra-class correlation coefficient = 0.63). The EQ-5D-3L appeared more sensitive to change over the 6-month period.
Our findings show that the EQ-5D-3L and HUI3 estimate different utility scores among nursing home residents. These differences should be taken into account, particularly when considering the implications of the cost-effectiveness of particular interventions and we conclude that the HUI3 is no better suited to measuring health-related quality of life in a nursing home population when compared to the EQ-5D-3L.
准确评估长期居住在养老院的老年人的生活质量变化至关重要。在养老院人群中,最常用且推荐用于评估与健康相关生活质量的多属性效用工具是三级欧洲五维度健康量表(EQ-5D-3L)。迄今为止,尚无使用健康效用指数第三版(HUI3)的研究。本研究的目的是比较EQ-5D-3L和HUI3在养老院人群中的一致性水平和对变化的敏感性。
在澳大利亚西部珀斯的一个养老院人群中,将EQ-5D-3L和HUI3评分作为护士主导的护理协调整群随机对照试验的一部分,在基线和6个月随访时进行测量。
在基线时,199名居民完成了两项测量,6个月随访时为177名。EQ-5D-3L的平均基线效用评分(0.45;95%可信区间0.41 - 0.49)和HUI3的平均基线效用评分(0.15;95%可信区间0.10 - 0.20)有显著差异(Wilcoxon符号秩检验,p<0.01),且两种工具的绝对评分之间的一致性为差到中等(组内相关系数 = 0.63)。EQ-5D-3L在6个月期间似乎对变化更敏感。
我们的研究结果表明,EQ-5D-3L和HUI3在养老院居民中估计的效用评分不同。应考虑这些差异,尤其是在考虑特定干预措施成本效益的影响时,并且我们得出结论,与EQ-5D-3L相比,HUI3在测量养老院人群与健康相关的生活质量方面并不更具优势。