Li William, Subedi Rogin, Madhira Bhaskara
Internal Medicine, SUNY Upstate Medical University, United States.
Internal Medicine, SUNY Upstate Medical University, United States.
Am J Emerg Med. 2017 Jun;35(6):941.e1-941.e2. doi: 10.1016/j.ajem.2017.01.012. Epub 2017 Jan 19.
Cardiac tamponade is a medical emergency consisting of an accumulation of fluid in the pericardial space which is rapidly progressing and fatal. Because cardiac tamponade is ultimately a clinical diagnosis, mindful consideration for atypical presentations is essential for the reduction of mortality in the acute setting. Our patient was a 77year-old female admitted after presenting with general malaise, weakness, somnolence, altered mental status and urinary incontinence found to have CML (chronic myeloid leukemia) on confirmatory bone marrow biopsy after suspicions arose from a leukocytosis of 34,000 cells per mcL with 85% neutrophils and elevated blasts (8%). Initial vital signs revealed mild tachycardia, mild tachypnea and blood pressure elevated to 162/84mm Hg along with a temperature of 38.7°C and oxygen saturation of 96% on 2l by nasal cannula. She received the standard of care for a community acquired pneumonia and was started on treatment with decitabine as further work-up was unremarkable. An abdominal CT performed for abdominal fullness later displayed a large pericardial effusion. Repeat echocardiography exhibited right atrial diastolic collapse, inferior vena cava dilatation (IVC) without inspiratory collapse >50% and the large pericardial effusion consistent with tamponade. The blood pressure remained hypertensive until she suddenly went into cardiac arrest after being intubated for a pericardial window and expired. Our case highlights the need to keep cardiac tamponade as a differential in the hypertensive individual with abdominal complaints as atypical presentations can obscure diagnosis, delay treatment and increase mortality.
心脏压塞是一种医疗急症,由心包腔内液体迅速积聚且进展迅速并可致命。由于心脏压塞最终是一种临床诊断,因此在急性情况下,认真考虑非典型表现对于降低死亡率至关重要。我们的患者是一名77岁女性,因全身不适、虚弱、嗜睡、精神状态改变和尿失禁入院,在白细胞计数为每微升34,000个细胞,中性粒细胞占85%且原始细胞升高(8%)引起怀疑后,经确诊性骨髓活检发现患有慢性粒细胞白血病(CML)。初始生命体征显示轻度心动过速、轻度呼吸急促,血压升至162/84mmHg,体温38.7°C,经鼻导管吸氧2升时血氧饱和度为96%。她接受了社区获得性肺炎的标准治疗,并开始使用地西他滨治疗,因为进一步检查无异常。后来因腹部胀满进行的腹部CT显示大量心包积液。重复超声心动图显示右心房舒张期塌陷、下腔静脉扩张(IVC)且吸气时无塌陷>50%,以及与心脏压塞一致的大量心包积液。血压一直处于高血压状态,直到她在因心包开窗插管后突然心脏骤停并死亡。我们的病例强调,对于有腹部症状的高血压患者,需要将心脏压塞作为鉴别诊断,因为非典型表现可能会掩盖诊断、延误治疗并增加死亡率。