Rosenzweig K E, Giraud P
Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, One Gustav L. Levy Place, Box 1236, 10029 New York, NY, USA.
Service d'oncologie radiothérapie, hôpital européen Georges-Pompidou, université Paris Descartes, Sorbonne Paris Cité, 20, rue Leblanc, 75015 Paris, France.
Cancer Radiother. 2017 Feb;21(1):73-76. doi: 10.1016/j.canrad.2016.09.009. Epub 2017 Feb 23.
The treatment of malignant pleural mesothelioma with radiation has always been a technical challenge. For many years, conventional radiation therapy was delivered after extrapleural pneumonectomy with acceptable results. Novel radiation treatment techniques, such as intensity modulated radiation therapy (IMRT) were introduced, but the early experience with IMRT demonstrated troubling toxicity. Recent reports from institutions have demonstrated that with greater experience, IMRT, both in the setting of extrapleural pneumonectomy or pleurectomy, can be delivered safely. A recent study, SAKK 17/04, questions the role of using radiation after extrapleural pneumonectomy.
用放射治疗恶性胸膜间皮瘤一直是一项技术挑战。多年来，常规放射治疗在胸膜外全肺切除术后进行，效果尚可。新型放射治疗技术，如调强放射治疗（IMRT）被引入，但IMRT的早期经验显示出令人担忧的毒性。来自各机构的最新报告表明，随着经验的增加，无论是在胸膜外全肺切除术还是胸膜切除术的情况下，IMRT都可以安全实施。最近的一项研究SAKK 17/04对胸膜外全肺切除术后使用放射治疗的作用提出了质疑。
