来自海洋海绵及其相关细菌的主要抗菌代表物。

Major Antimicrobial Representatives from Marine Sponges and/or Their Associated Bacteria.

作者信息

He Fei, Mai Linh H, Gardères Johan, Hussain Amjad, Erakovic Haber Vesna, Bourguet-Kondracki Marie-Lise

机构信息

Laboratoire Molécules de Communication et Adaptation des Micro-organismes, UMR 7245 MNHN-CNRS, Muséum National d'Histoire Naturelle, 57 rue Cuvier (C.P. 54), 75005, Paris, France.

Fidelta d.o.o., Prilaz baruna Filipovića 29, 10000, Zagreb, Croatia.

出版信息

Prog Mol Subcell Biol. 2017;55:35-89. doi: 10.1007/978-3-319-51284-6_2.

DOI:10.1007/978-3-319-51284-6_2

PMID:28238035

Abstract

The rapid emergence of resistant bacteria during the last 20 years has stimulated research efforts in order to overcome this thorny problem. Marine sponges and their associated bacteria, which have been proven to be a source of bioactive natural products, have appeared as a promising opportunity to identify new antibiotic compounds. An overview of the major antibacterial compounds isolated from marine sponges and/or their associated bacteria is presented in this chapter, highlighting new potential antibiotics.

摘要

在过去20年中，耐药细菌的迅速出现激发了相关研究工作，以攻克这一棘手问题。海洋海绵及其相关细菌已被证明是生物活性天然产物的来源，它们成为了鉴定新型抗生素化合物的一个有前景的机会。本章概述了从海洋海绵和/或其相关细菌中分离出的主要抗菌化合物，重点介绍了新的潜在抗生素。