Oztas Mert, Ugurlu Serdal, Aydin Ovgu
Division of Internal Medicine, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey.
Division of Rheumatology, Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey.
Rheumatol Int. 2017 Jul;37(7):1217-1219. doi: 10.1007/s00296-017-3658-9. Epub 2017 Feb 25.
A 49-year-old man with no previous history of musculoskeletal or cutaneous problems who had a myocardial infarction (MI) was treated with atorvastatin, prasugrel, enoxaparine, and diltiazem following percutaneous coronary intervention. He was referred to our rheumatology outpatient clinic for rash and papules on the knuckles, face, and neck, as well as proximal muscle weakness. In the physical examination, a reddish rash on the face and Gottron's papules on the knuckles were detected. The skin biopsy performed indicated interface dermatitis with hydropic degeneration of basal keratinocytes, supporting the clinical impression of dermatomyositis. He was started on prednisolone 1 mg/kg/day. After 30 days of prednisolone therapy, all symptoms disappeared.
一名49岁男性，既往无肌肉骨骼或皮肤问题病史，因心肌梗死（MI）在经皮冠状动脉介入治疗后接受阿托伐他汀、普拉格雷、依诺肝素和地尔硫䓬治疗。他因指关节、面部和颈部出现皮疹和丘疹以及近端肌无力被转诊至我们的风湿病门诊。体格检查发现面部有红色皮疹，指关节有Gottron丘疹。进行的皮肤活检显示为界面性皮炎伴基底角质形成细胞水肿性变性，支持皮肌炎的临床诊断。开始给予泼尼松龙1mg/kg/天治疗。泼尼松龙治疗30天后，所有症状消失。
