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通过饮食和运动改善生活方式(LIFE)研究参与者的招募及基线特征

Recruitment and Baseline Characteristics of Participants in the Lifestyle Improvement Through Food and Exercise (LIFE) Study.

作者信息

Lynch Elizabeth, Mack Laurin J, Karavolos Kelly, Avery Elizabeth, Liebman Rebecca, Keim Kathryn S, Glover Crystal M, Fogelfeld Leon

出版信息

J Health Care Poor Underserved. 2017;28(1):463-486. doi: 10.1353/hpu.2017.0034.

DOI:10.1353/hpu.2017.0034
PMID:28239013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5777146/
Abstract

African Americans experience poorer diabetes outcomes than non-Hispanic Whites. Few clinical trials of diabetes self-management interventions specifically target African Americans, perhaps due to well-documented barriers to recruitment in this population. This paper describes strategies used to successfully recruit 211 low-income African Americans from community clinics of a large, urban public hospital system to a randomized clinical trial of an 18-month diabetes self-management intervention. Diabetes-related physiological, psychosocial, and behavioral characteristics of the sample are reported. The sample was 77% female, mean age = 55, mean A1C = 8.5%, 39% low health literacy, 28.4% moderate/severe depression, and 48.3% low adherence. Participants ate a high-fat diet with low vegetable consumption. Relative to males, females had higher BMI, depression, and stress, and better glycemic control, less physical activity, and less alcohol consumption. Males consumed more daily calories, but females consumed a greater proportion of carbohydrates. Gender-specific diabetes self-management strategies may be warranted in this population.

摘要

非裔美国人的糖尿病治疗效果比非西班牙裔白人更差。很少有糖尿病自我管理干预的临床试验专门针对非裔美国人,这可能是由于该人群中存在有充分记录的招募障碍。本文描述了从一个大型城市公立医院系统的社区诊所成功招募211名低收入非裔美国人参加一项为期18个月的糖尿病自我管理干预随机临床试验所采用的策略。报告了样本的糖尿病相关生理、心理社会和行为特征。样本中77%为女性,平均年龄 = 55岁,平均糖化血红蛋白(A1C)= 8.5%,39%健康素养低,28.4%有中度/重度抑郁,48.3%依从性低。参与者饮食中脂肪含量高,蔬菜摄入量低。相对于男性,女性的体重指数(BMI)、抑郁程度和压力更高,血糖控制更好,身体活动较少,饮酒较少。男性每日摄入的卡路里更多,但女性摄入的碳水化合物比例更高。在这一人群中可能需要针对性别制定糖尿病自我管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ccc/5777146/290009770a14/nihms934543f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ccc/5777146/290009770a14/nihms934543f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ccc/5777146/290009770a14/nihms934543f1.jpg

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Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study.糖尿病老年患者危险因素控制的患病率及种族差异:社区动脉粥样硬化风险研究
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性别差异在 2 型糖尿病患者整个生命周期的体力活动中:系统评价和荟萃分析。
Diabetes Care. 2022 Sep 1;45(9):2163-2177. doi: 10.2337/dc22-0576.
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Randomized Trial of a Lifestyle Intervention for Urban Low-Income African Americans with Type 2 Diabetes.一项针对城市低收入非裔美国 2 型糖尿病患者的生活方式干预的随机试验。
J Gen Intern Med. 2019 Jul;34(7):1174-1183. doi: 10.1007/s11606-019-04894-y. Epub 2019 Apr 8.
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通过饮食与运动改善生活方式(LIFE)研究的设计:一项针对安全网健康中心的非裔美国患者2型糖尿病自我管理的随机对照试验。
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