一例上颌窦无色素性恶性黑色素瘤伴口内侵犯
A Case of Amelanotic Malignant Melanoma of the Maxillary Sinus Presented with Intraoral Extension.
作者信息
Singhvi Abhishek, Joshi Ashish
机构信息
Department of Oral and Maxillofacial Pathology, Vyas Dental College and Hospital, Kudi Haud, Pali Road, Jodhpur PIN 342008, Rajasthan, India.
Post graduate student, Department of Oral and Maxillofacial Pathology, Vyas Dental College and Hospital, Kudi Haud, Pali Road, Jodhpur PIN 342008, Rajasthan, India.
出版信息
Malays J Med Sci. 2015 Sep;22(5):89-92.
Melanoma of the sinonasal cavity has a high incidence of amelanotic presentation. Its diagnosis is difficult for clinicians and pathologists because of its hidden location and lack of pigmentation at the microscopic level. We reported a case of amelanotic melanoma of the maxillary sinus that showed aggressive extension to the oral cavity after extraction of the maxillary tooth. Histologically, the lesion resembled a plasmacytoid tumour. Diagnosis was made through the positive immunohistochemical staining for S100 and HMB-45.
鼻窦黑色素瘤无色素表现的发生率很高。由于其位置隐匿且在微观层面缺乏色素沉着，临床医生和病理学家对其诊断都很困难。我们报告了一例上颌窦无色素黑色素瘤病例，该病例在上颌牙拔除后显示出向口腔的侵袭性扩展。组织学上，病变类似于浆细胞样肿瘤。通过S100和HMB - 45免疫组化染色阳性做出诊断。
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