van Marcke C, Seront E, Docquier C, Filleul B
Department of Medical Oncology, Hôpital de Jolimont, La Louvière, Belgium.
Department of Internal Medicine, Hôpital de Jolimont, La Louvière, Belgium.
Clin Exp Dermatol. 2017 Apr;42(3):328-330. doi: 10.1111/ced.13071. Epub 2017 Feb 27.
Palmar fasciitis and polyarthritis syndrome (PFPAS) is an uncommon disorder characterized by diffuse inflammation of the palmar fascia, tendon sheaths, and joints of the fingers and wrists, which rapidly progresses to flexion contracture of the hands. This paraneoplastic syndrome, originally linked to ovarian carcinoma, has also been associated with multiple different malignancies. As PFPAS usually precedes the detection of cancer, its symptoms should raise the suspicion of an underlying malignancy and should be thoroughly investigated.
掌腱膜和多关节炎综合征（PFPAS）是一种罕见的疾病，其特征为掌腱膜、腱鞘以及手指和手腕关节的弥漫性炎症，病情会迅速发展为手部屈曲挛缩。这种副肿瘤综合征最初与卵巢癌有关，也与多种不同的恶性肿瘤相关。由于PFPAS通常在癌症被发现之前出现，其症状应引起对潜在恶性肿瘤的怀疑，并应进行全面调查。
