From the Department of Radiology, University of Tennessee Graduate School of Medicine, University of Tennessee Medical Center, Knoxville, TN.
Clin Nucl Med. 2017 May;42(5):373-374. doi: 10.1097/RLU.0000000000001613.
The usage of PET/CT to monitor patients with hepatocellular carcinoma following Y radioembolization has increased; however, image quality is often poor because of low count efficiency and respiratory motion. Motion can be corrected using gating techniques but at the expense of additional image noise. Amplitude-based gating has been shown to improve quantification in FDG PET, but few have used this technique in Y liver imaging. The patients shown in this work indicate that amplitude-based gating can be used in Y PET/CT liver imaging to provide motion-corrected images with higher estimates of activity concentration that may improve posttherapy dosimetry.
正电子发射断层扫描/计算机断层扫描（PET/CT）在 Y 放射性栓塞治疗肝癌后用于监测患者的应用有所增加；然而，由于低计数效率和呼吸运动，图像质量通常较差。运动可以通过门控技术来校正，但这会增加额外的图像噪声。基于幅度的门控已被证明可以提高 FDG PET 的定量准确性，但很少有人在 Y 肝脏成像中使用这种技术。本研究中的患者表明，基于幅度的门控可用于 Y 放射性核素 PET/CT 肝脏成像，以提供运动校正图像，更高的活性浓度估计值，这可能改善治疗后剂量学。
