Cheng Wei, Yu Zhao, Liu Shelan, Zhang Xueying, Wang Xiaoxiao, Cai Jian, Ling Feng, Chen Enfu
Zhejiang Provincial Centre for Disease Control and Prevention, Hangzhou 310051, China.
Field Epidemiology Training Programme of Zhejiang Province, Hangzhou 310051, China.
Int J Environ Res Public Health. 2017 Feb 22;14(2):217. doi: 10.3390/ijerph14020217.
Given the rapid rate of global spread and consequently healthcare costs related to influenza, surveillance plays an important role in monitoring the emerging pandemics in China. However, the characteristics of influenza in Southeast of China haven't been fully studied. Our study use the surveillance data collected from 16 sentinel hospitals across Zhejiang Province during March 2011 through June 2015, including the demographic information and respiratory specimens from influenza-like illness (ILI) patients and severe acute respiratory illness (SARI) patients. As analysis results, most SARI and ILI patients were in the age group of 0-4 years old (62.38% of ILI and 71.54% of SARI). The respiratory specimens have statistically significantly higher positive rate for influenza among ILI patients than that among SARI patients ( 0.001). The comparison between ILI patients and SARI patients shows no statistically significantly difference in detecting influenza virus type and influenza A virus subtype. The SARI and ILI patients were found to be positively correlated for overall positive rate (r = 0.63, < 0.001), the weekly percentage of A(H1N1)pdm09 (r = 0.51, < 0.001), influenza B virus (r = 0.17, = 0.013), and A/H3N2 (r = 0.43, < 0.001) among all the positive numbers. Our study demonstrated that the activities of influenza virus, including its subtypes, had a similar temporal pattern between ILI and SARI cases.
鉴于流感在全球的快速传播速度以及由此产生的医疗费用，监测在中国监测新出现的大流行病方面发挥着重要作用。然而，中国东南部流感的特征尚未得到充分研究。我们的研究使用了2011年3月至2015年6月期间从浙江省16家哨点医院收集的监测数据，包括流感样疾病（ILI）患者和严重急性呼吸疾病（SARI）患者的人口统计学信息和呼吸道标本。分析结果显示，大多数SARI和ILI患者年龄在0至4岁组（ILI患者占62.38%，SARI患者占71.54%）。ILI患者呼吸道标本中流感的阳性率在统计学上显著高于SARI患者（P<0.001）。ILI患者和SARI患者在检测流感病毒类型和甲型流感病毒亚型方面没有统计学上的显著差异。发现SARI和ILI患者在总体阳性率（r = 0.63，P<0.001）、A（H1N1）pdm09的每周百分比（r = 0.�1，P<0.001）、乙型流感病毒（r = 0.17，P = 0.013）和所有阳性病例中的A/H3N2（r = 0.43，P<0.001）方面呈正相关。我们的研究表明，流感病毒的活动，包括其亚型，在ILI和SARI病例之间具有相似的时间模式。
