Dong Yan, Liao Jiangquan, Yao Kuiwu, Jiang Wenrui, Wang Jie
Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Evid Based Complement Alternat Med. 2017;2017:1381732. doi: 10.1155/2017/1381732. Epub 2017 Jan 24.
Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is related to many cardiac and cerebral vascular diseases, especially stroke. It can therefore increase cardiovascular mortality and all-cause death. The current treatments of AF remain to be western drugs and radiofrequency ablation which are limited by the tolerance of patients, adverse side effects, and high recurrence rate, especially for the elderly. On the contrary, traditional Chinese medicine (TCM) with long history of use involves various treatment methods, including Chinese herbal medicines (CHMs) or bioactive ingredients, Chinese patent medicines, acupuncture, Qigong, and Tai Chi Chuan. With more and more researches reported, the active roles of TCM in AF management have been discovered. Then it is likely that TCM would be effective preventive means and valuable additional remedy for AF. The potential mechanisms further found by numerous experimental studies showed the distinct characteristics of TCM. Some CHMs or bioactive ingredients are atrial-selective, while others are multichannel and multifunctional. Therefore, in this review we summarized the treatment strategies reported in TCM, with the purpose of providing novel ideas and directions for AF management.
心房颤动(AF)是最常见的心律失常,与许多心脑血管疾病相关,尤其是中风。因此,它会增加心血管疾病死亡率和全因死亡率。目前AF的治疗方法仍然是西药和射频消融,但这些方法受到患者耐受性、不良副作用和高复发率的限制,尤其是对老年人而言。相反,有着悠久使用历史的传统中药(TCM)涉及多种治疗方法,包括中草药(CHMs)或生物活性成分、中成药、针灸、气功和太极拳。随着越来越多的研究报道,已发现中药在AF管理中的积极作用。那么中药很可能是AF有效的预防手段和有价值的辅助治疗方法。众多实验研究进一步发现的潜在机制显示了中药的独特特征。一些中草药或生物活性成分具有心房选择性,而其他的则具有多通道和多功能性。因此,在本综述中,我们总结了中药报道的治疗策略,目的是为AF管理提供新的思路和方向。