* Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, The Second Clinical Medical College of Guangzhou University of Chinese, Medicine Guangzhou, Guangdong 510120, P. R. China.
† The Postdoctoral Research Station, Guangzhou University of Chinese Medicine Guangzhou, Guangdong 510120, P. R. China.
Am J Chin Med. 2018;46(5):953-970. doi: 10.1142/S0192415X18500507. Epub 2018 Jul 9.
Although lots of great achievements have been gained in the battle against cancer during the past decades, cancer is still the leading cause of death in the world including in developing countries such as China. Traditional Chinese medicine (TCM) is popular in Chinese and East Asian societies as well as some other Western countries and plays an active role in the modern healthcare system including patients with cancer, which may act as a potential effective strategy in treating human cancers. In this review, we aimed to introduce the mechanisms of TCM compound, as an option of individualized therapy, in treating cancer patients from the perspective of both Chinese and Western medicine. In the view of traditional Chinese medicine theory, individualized treatment for human cancers based on syndrome type benefits the cancer patients with personalized conditions. Balancing Qi, Xue, Yin and Yang, eliminating phlegm and removing dampness is how TCM compound functions on cancer patients. While in the view of Western medicine, inhibiting cancer cell growth and metastasis as well as improving immune status is how herbal compounds act on cancer patients. We also summarized the applications of TCM compound in human cancers, which will shed light on the clinical application of TCM compound on patients with cancer. TCM compound could be used as a complementary and alternative medicine (CAM) in human cancers. It could be applied in cancer patients with cancer-related fatigue (CRF). In addition, it is a good method for alleviating the side effects of both radiotherapy and chemotherapy. Therefore, TCM compound plays a critical role in treating patients with cancer, which has a promising strategy in the field of cancer management.
尽管在过去几十年的抗癌斗争中取得了许多重大成就，但癌症仍然是包括中国在内的发展中国家的主要死亡原因。中医药在华人及东亚社会以及其他一些西方国家广受欢迎，并在包括癌症患者在内的现代医疗体系中发挥着积极作用，这可能是治疗人类癌症的一种潜在有效策略。在这篇综述中，我们旨在从中医和西医的角度介绍中药复方作为个体化治疗选择治疗癌症患者的机制。从中医理论的角度来看，基于证型的个体化治疗对具有个性化条件的癌症患者有益。平衡气、血、阴、阳，化痰除湿是中药复方对癌症患者的作用机制。而从西医的角度来看，抑制癌细胞生长和转移以及改善免疫状态是草药化合物对癌症患者的作用机制。我们还总结了中药复方在人类癌症中的应用，这将为癌症患者应用中药复方提供参考。中药复方可作为癌症患者的补充和替代医学（CAM）。它可用于癌症相关性疲劳（CRF）的癌症患者。此外，它是缓解放疗和化疗副作用的好方法。因此，中药复方在治疗癌症患者方面发挥着关键作用，在癌症管理领域具有广阔的应用前景。
