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当代损伤控制手术的结果:对80例右上腹严重腹部损伤患者进行了分析。

Contemporary damage control surgery outcomes: 80 patients with severe abdominal injuries in the right upper quadrant analyzed.

作者信息

Hommes M, Chowdhury S, Visconti D, Navsaria P H, Krige J E J, Cadosch D, Nicol A J

机构信息

Department of Surgery, Trauma Centre, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

Department of Surgery, University of Cape Town, Cape Town, South Africa.

出版信息

Eur J Trauma Emerg Surg. 2018 Feb;44(1):79-85. doi: 10.1007/s00068-017-0768-8. Epub 2017 Feb 27.

Abstract

BACKGROUND

Damage control laparotomy (DCL) is a well-established surgical strategy in the management of the severely injured abdominal trauma patients. The selection of patients by intra-abdominal organs involvement for DCL remains controversial. The aim of this study was to assess the injury to the abdominal organs that causing severe metabolic failure, needing DCL.

METHODS

Severely injured abdominal trauma patients with a complex pattern of injuries were reviewed over a 52-month period. They were divided into DCL and definitive repair (DR) group according to the operative strategy. Factors identifying patients who underwent a DCL were analyzed and evaluated.

RESULTS

Twenty-five patients underwent a DCL, and 55 patients had DR. Two patients died before or during surgery. The number and severity of overall injuries were equally distributed in the two groups of patients. Patients who underwent a DCL presented more frequently hemodynamically unstable (p = 0.02), required more units of blood (p < 0.0001) and intubation to secure the airway (p < 0.0001). The onset of metabolic failure was more profound in these group of patients than DR group. The mean Basedeficit was - 7.0 and - 3.8, respectively, (p = 0.003). Abdominal vascular (p = 0.001) and major liver injuries (p = 0.006) were more frequently diagnosed in the DCL group. The mortality, complications (p < 0.0001), hospital (p < 0.0001), and ICU stay (p < 0.009) were also higher in patients with DCL.

CONCLUSION

In severely injured with an intricate pattern of injuries, 31% of the patients required a DCL with 92% survival rate. Severe metabolic failure following significant liver and abdominal vascular injuries dictates the need for a DCL and improves outcome in the current era.

摘要

背景

损伤控制剖腹术(DCL)是治疗严重腹部创伤患者的一种成熟的手术策略。根据腹腔内器官受累情况选择DCL患者仍存在争议。本研究的目的是评估导致严重代谢衰竭、需要进行DCL的腹部器官损伤情况。

方法

回顾了52个月期间受伤模式复杂的严重腹部创伤患者。根据手术策略将他们分为DCL组和确定性修复(DR)组。分析并评估了确定接受DCL患者的因素。

结果

25例患者接受了DCL,55例患者进行了DR。2例患者在手术前或手术期间死亡。两组患者的总体损伤数量和严重程度分布相同。接受DCL的患者血流动力学不稳定的情况更常见(p = 0.02),需要更多单位的血液(p < 0.0001)以及进行气管插管以确保气道安全(p < 0.0001)。这组患者的代谢衰竭发作比DR组更严重。平均碱缺失分别为-7.0和-3.8(p = 0.003)。DCL组更常诊断出腹部血管损伤(p = 0.001)和严重肝损伤(p = 0.006)。DCL患者的死亡率、并发症(p < 0.0001)、住院时间(p < 0.0001)和重症监护病房停留时间(p < 0.009)也更高。

结论

在受伤模式复杂的严重创伤患者中,31%的患者需要进行DCL,生存率为92%。严重肝脏和腹部血管损伤后出现的严重代谢衰竭决定了需要进行DCL,并在当前时代改善了治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6500/5808053/f0cd90c613f7/68_2017_768_Fig1_HTML.jpg

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