Nicol A J, Hommes M, Primrose R, Navsaria P H, Krige J E J
Department of Surgery, Trauma Unit, Ward C14, Groote Schuur Hospital, Anzio Road, Observatory, Cape Town, 7925, South Africa.
World J Surg. 2007 Mar;31(3):569-74. doi: 10.1007/s00268-006-0070-0.
Packing for complex liver injuries has been associated with an increased risk of abdominal sepsis and bile leaks. The aim of the present study was to determine the optimum timing of pack removal and to assess whether the total duration of packing increases the incidence of these complications.
The study was based on a retrospective review of all patients requiring liver packing over an 8-year period in a level 1 trauma center.
Ninety-three (17%) of 534 liver injuries identified at laparotomy required perihepatic packing. Penetrating and blunt trauma occurred in 72 (77%) and 21 (23%), respectively. The mean total duration of packing was 2.4 days (range: 0.5-6.0 days). There was no association between the total duration of packing and the development of liver-related complications (P = 0.284) or septic complications (P = 0.155). Early removal of packs at 24 h was associated with a higher rate of re-bleeding than removal of packs at 48 h (P = 0.006).
The total duration of liver packing does not result in an increase in septic complications or bile leaks. The first re-look laparotomy should only be performed after 48 h. An early re-look at 24 h is associated with re-bleeding and does not lead to early removal of liver packs.
对复杂肝损伤进行填塞与腹部感染和胆漏风险增加相关。本研究的目的是确定取出填塞物的最佳时机,并评估填塞的总时长是否会增加这些并发症的发生率。
本研究基于对一家一级创伤中心8年间所有需要进行肝脏填塞的患者的回顾性分析。
剖腹手术中确诊的534例肝损伤患者中有93例(17%)需要进行肝周填塞。穿透伤和钝性伤分别占72例(77%)和21例(23%)。填塞的平均总时长为2.4天(范围:0.5 - 6.0天)。填塞总时长与肝脏相关并发症的发生(P = 0.284)或感染性并发症的发生(P = 0.155)之间无关联。与48小时取出填塞物相比,24小时早期取出填塞物的再出血率更高(P = 0.006)。
肝脏填塞的总时长不会导致感染性并发症或胆漏增加。首次再次剖腹探查应在48小时后进行。24小时进行早期再次探查与再出血相关,且不会导致肝脏填塞物的早期取出。